Cellular Physiology and Neurophysiology

Answers to study problems

Chapter 2 1. The relationship between the distance and time of diffusion is d ; that is, the distance diffused is proportional to the square root of time (e.g., for three-dimensional diffusion, ). One way to solve the problem is…

Summary of elementary circuit theory

Cell membranes are modeled with electrical circuits The plasma membrane can be modeled as an electrical circuit. Fig. AppD.1 A is a schematic view of the structure of a biological membrane with a single open K + –selective ion channel.…

A mathematical refresher

Exponents Definition of exponentiation Multiplying the number 3 by itself four times gives 3×3×3×3= 81 3 × 3 × 3 × 3 = 81 which can be written more simply with the shorthand notation 34= 81 3 4 = 81…

Epilogue

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Mechanics of muscle contraction

Objectives 1. Explain how a skeletal muscle twitch and a tetanus are generated. 2. Describe how muscle contractile force can be varied. 3. Describe the mechanical properties of muscle that are characterized by the length-tension relationship and the force-velocity relationship.…

Excitation-contraction coupling in muscle

Objectives 1. Compare and contrast the mechanisms of excitation-contraction coupling in skeletal, cardiac, and smooth muscle cells. 2. For skeletal muscle, describe: a. How movement of a voltage sensor couples sarcolemmal depolarization to the opening of SR Ca 2+ release…

Molecular motors and the mechanism of muscle contraction

Objectives 1. List the common principles that apply to all molecular motors: myosin, kinesin, and dynein. 2. Describe the structure of a skeletal muscle cell and the organization of its contractile elements, and compare and contrast this with the structure…