Blumgart's Surgery of the Liver, Biliary Tract and Pancreas

Advances in systemic therapy for hepatocellular carcinoma

Overview Hepatocellular carcinoma (HCC) represents a challenging malignancy of global importance (see Chapter 89 ). It is the fifth most common solid tumor in terms of incidence and the third leading cause of cancer-related death worldwide. Its incidence mirrors that…

Regional chemotherapy for liver tumors

Overview The liver is a unique organ with a rich dual blood supply (see Chapter 2 ) and serves as a target organ for many tumor metastases. As the portal vein drains the gastrointestinal (GI) tract, malignancies arising from these…

Cryotherapy and ethanol injection

Cryotherapy Introduction Hepatic ablative techniques remain an important tool in the armamentarium against both primary and metastatic liver tumors. Liver resection continues to be the gold standard in management; however, ablative therapies are useful for patients with limited disease and…