Summary of Key Points Incidence 60,000 estimated new cases per year. Approximately 10,400 deaths per year from the disease. Endometrioid adenocarcinoma arises in the endometrium and accounts for approximately 90% of cases. Biological Characteristics Median age is 63 years. The…
Summary of Key Points Cervical Cancer An estimated 12,990 new cases of invasive cervical cancer were anticipated in 2016 in the United States, with 4120 deaths projected. Seventy-five percent to 80% are squamous cell carcinomas. Since the advent of cytologic…
Summary of Key Points Incidence Testicular cancer comprises 1% of all male malignancies, accounting for over 8000 new cases a year in the United States. It is the most common malignancy in men aged 15 to 35 years. Germ cell…
Summary of Key Points Incidence Penile cancer is rare in developed countries but is responsible for a large proportion of solid tumors in males where sanitation and medical care are poor. Biologic Characteristics Most penile cancers are squamous cell carcinomas,…
Summary of Key Points Incidence Prostate cancer is the most commonly diagnosed life-threatening cancer in men (180,890 cases and 26,120 deaths in 2016). Small prostate cancers are present in 29% of men between ages 30 and 40 and 64% of…
Summary of Key Points Incidence Worldwide, bladder cancer is diagnosed at a rate of approximately 429,800 cases each year and causes 165,100 deaths. In the United States, it is the fourth most common cancer in men. In 2018 there were…
Summary of Key Points Renal cell carcinoma (RCC) accounts for 4% to 5% of malignancies in adults. Cigarette smoking (in more than 20% of cases) and obesity (in more than 30%) are established causal factors for RCC. Four percent of…
Summary of Key Points Pancreatic adenocarcinoma is the fourth leading cause of cancer-related death. The overall 5-year survival rate for all patients is less than 5%: 15% to 20% of patients present with resectable or borderline resectable disease with a…
Summary of Key Points Liver Cancer There is a continued rise of hepatocellular carcinoma (HCC) incidence, especially in the Western hemisphere. HCC main risk factors are hepatitis B, hepatitis C, alcohol use, and nonalcoholic steatohepatitis. Screening programs continue to evolve…
Summary of Key Points Incidence It was estimated that there were 8580 anal squamous cell carcinomas diagnosed and 1160 deaths from this disease in the United States in 2018. The age-adjusted incidence rate is 1.7 per 100,000 men and women…