Summary of Key Points Incidence There were 19,950 new cases of acute myeloid leukemia (AML) and 6590 new cases of acute lymphocytic leukemia (ALL) in the United States in 2016, resulting in 10,430 deaths from AML and 1430 from ALL.…
Summary of Key Points Incidence Malignant lymphoma, which comprises both Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL), is the third most common malignancy in childhood. Among children younger than age 15 years, there is a slight predominance of NHL; HL…
Summary of Key Points Incidence Leukemia is the most common childhood cancer, accounting for 30% of cancers occurring before age 15 years and 25% before age 20 years. Acute lymphoblastic leukemia (ALL) accounts for 75% to 80% of all cases…
Summary of Key Points Osteosarcoma The incidence of osteosarcoma is 5 new cases per 1 million population per year among children and adolescents (up to 19 years). Osteosarcoma is the most common bone tumor in children and adolescents. Other lytic…
Summary of Key Points Incidence Carcinoma of unknown primary is a diverse group of heterogeneous cancers that accounts for about 2% to 4% of all cancers. Evaluation There is not universal agreement on the extent of the appropriate initial evaluation…
Summary of Key Points Incidence and Epidemiology Annually, 12,390 new cases occur in the United States—fewer than 1%–2% of cancer diagnoses. No specific etiologic agent is identifiable in the majority of cases. Occasional cases are related to previous radiation, chemical…
Summary of Key Points Incidence and Epidemiology More than 3000 new cases of bone sarcoma are diagnosed annually in the United States. No specific etiologic agents are identified in the majority of cases. Secondary neoplasms are related to known oncogenic…
Summary of Key Points Incidence and Epidemiology Breast cancer is the most frequently diagnosed cancer in women in the United States, accounting for an estimated 268,670 new cases of invasive breast carcinoma, 63,960 new cases of in situ carcinoma, and…
Summary of Key Points Incidence and Epidemiology The incidence of complete hydatidiform mole is approximately 1 in 1200 pregnancies in the United States. The incidence of partial hydatidiform mole is approximately 1 in 650 pregnancies. Repeat moles occur in approximately…
Summary of Key Points Ovarian cancer is the second most common gynecologic malignancy, but it is the leading cause of gynecologic cancer-related deaths in the United States. There are many different histologic subtypes of ovarian cancer. Among these, high-grade serous…