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Out-of-office blood pressure (BP) monitoring is the assessment of BP outside of the clinic setting using either ambulatory BP monitoring (ABPM) or self-monitoring of BP at home, also known as home BP monitoring (HBPM).
Out-of-office BP monitoring is performed to confirm the diagnosis of hypertension and to assist with titration of antihypertensive medications. Out-of-office BP monitoring is particularly useful for identifying discrepancies between BPs measured in versus outside of the clinic, including masked and white coat hypertension ( Fig. 2.1 ).
Masked hypertension (MH) and masked uncontrolled hypertension (MUCH) :
Defined as normal clinic BP with elevated out-of-office BP
MH occurs in patients not yet on antihypertensive therapy
MUCH occurs in patients on antihypertensive therapy
Associated with similarly elevated cardiovascular risk as sustained hypertension
Most common in men, individuals of African descent, individuals with chronic kidney disease, and individuals with obstructive sleep apnea
Consider screening patients with:
Evidence of target organ damage disproportionate to their degree of BP control in the clinic
Clinic BPs less than 10 mm Hg below their goal
Labile clinic BPs
White coat hypertension (WCH) and white coat effect (WCE) :
Defined as elevated clinic BP with normal out-of-office BP
WCH occurs in patients not yet on antihypertensive therapy
WCE occurs in patients on antihypertensive therapy
WCH is associated with:
Elevated cardiovascular risk that is lower in magnitude than sustained hypertension
High risk of transitioning to sustained hypertension
WCE is not associated with elevated cardiovascular risk
Most common in women, children, older adults, and patients with apparent treatment resistant hypertension
Consider screening in patients with:
Apparent treatment resistant hypertension
Treated hypertension and symptoms of low BPs outside of the office
Labile clinic BPs
Newly elevated clinic BPs
ABPM is a noninvasive method of out-of-office BP monitoring in which BPs are measured repeatedly over a 24- to 48-hour period, during routine daily activities and sleep, using a fully automated device.
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