Altered Mental Status in a Patient With Insulin-Dependent Diabetes


Case Study

A rapid response event was initiated for a patient with a blood glucose reading by finger stick of <10 mg/dL. On arrival of the rapid response team, the patient was somnolent but arousable to tactile stimuli. Nursing staff reported that the patient was a 75-year-old male with a history of end-stage renal disease on hemodialysis, type 2 diabetes mellitus, and congestive heart failure, who was admitted to the hospital for management of volume overload in the setting of missed dialysis. The patient had a malfunctioning atrioventricular (AV) fistula and was scheduled for fistula repair. He had been made nil per os (NPO) the night prior. It was noted that he received two-thirds of his usual dose of long-acting subcutaneous insulin and three units of short-acting insulin with a bedtime snack last evening. The patient’s nurse noted that the patient has mentioned that his diabetes was difficult to control, and he often experienced wide fluctuations in his blood glucose.

Vital Signs

  • Temperature: 98.9 °F, axillary

  • Blood Pressure: 105/85 mmHg

  • Heart Rate: 110 beats per min (bpm) – sinus tachycardia on telemetry

  • Respiratory Rate: 12 breaths per min

  • Pulse Oximetry: 98% oxygen saturation on room air

Focused Physical Examination

A quick exam showed a frail elderly gentleman lying in bed with his eyes closed. He was arousable to medium pressure sternal rub, was protecting his airway, and was able to answer simple yes/no questions. However, he would quickly return to his somnolent state once the verbal and tactile stimulation was withdrawn. His pupils were equal and reactive to light. He moved all his extremities spontaneously but was unable to follow complex commands. His skin was clammy to touch, and his heart sounds revealed tachycardia and a flow murmur because of AV fistula. His chest was clear bilaterally.

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