Adenocarcinoma of the Fallopian Tube


D efinition Adenocarcinoma arising in the tubal mucosa.

Clinical Features

Epidemiology

  • Historically a small fraction (5% or less) of pelvic serous carcinomas relative to the ovary; however, with the attention being paid to the distal tube (using the section and extensively examine the fimbriated end [SEE-FIM] protocol) as a source of many high-grade serous carcinomas, the incidence is presumed to be much higher.

  • Linked to chronic tubal inflammation.

  • Up to 30% have been reported to be associated with BRCA1 or BRCA2 germ-line mutations.

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