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Polynucleated Atypia of the Vulva


D efinition —A reactive epithelial process seen in skin or vulva characterized by a cytoskeletal defect with accumulation of nuclei in individual cells (multinucleation).

Clinical Features

Epidemiology

  • No particular demographic other than an association with nonspecific, chronic, irritative, or inflammatory changes in the vulva. Similar changes can be seen in cutaneous dermatoses.

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