Eosinophilic Gastroenteritis and Esophagitis

Terminology

• Inflammatory disease of GI tract characterized by tissue eosinophilia that can involve all layers of wall

  • "Eosinophilic gastroenteritis" is misnomer; can affect any portion of GI tract

• Requires 4 criteria for diagnosis

  • Presence of GI symptoms

  • Biopsy proof of eosinophilic infiltration of 1 or more areas of GI tract

  • Absence of eosinophilic involvement of multiple organs outside GI tract

  • Absence of parasitic infestation