Varicella Zoster


D efinition —Infection by the neurotropic varicella-zoster virus (VZV), an alpha-herpesvirus.

Clinical Features

Epidemiology

  • Primary VZV infection, commonly known as chickenpox, occurs predominantly in children.

  • Recurrences occur later in life.

  • Severe, recurrent infections can be seen in the setting of immunodeficiency.

  • Herpes zoster (shingles) is the secondary manifestation of VZV infection.

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