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D efinition —Infection by the neurotropic varicella-zoster virus (VZV), an alpha-herpesvirus.
Primary VZV infection, commonly known as chickenpox, occurs predominantly in children.
Recurrences occur later in life.
Severe, recurrent infections can be seen in the setting of immunodeficiency.
Herpes zoster (shingles) is the secondary manifestation of VZV infection.
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