Treatment of Aortic Graft Infection with Autologous Femoral Vein


There are no simple solutions to aortic graft infection, but a thoughtful approach to the surgical treatment of this condition minimizes the risk of major morbidity and mortality. No single operation is appropriate for all patients, so a working knowledge of the various options is critical to optimize outcomes.

Graft Excision

Eradication of the infection requires a combination of graft excision, wide débridement, and adjunctive antimicrobial therapy. Partial graft excision has been advocated for infections that appear on imaging to be localized to a single limb of an aortobifemoral bypass (AFB). Our extensive experience with aortic graft infections suggests that recurrent infection is not uncommon with this approach.

Options for Reconstruction

The options for aortic reconstruction after graft excision include extra-anatomic bypass and in-situ reconstruction. There are advantages and disadvantages of both approaches ( Table 1 ).

TABLE 1
Reconstruction Options After Excision of Infected Aortic Grafts
Reconstruction Option Advantages Disadvantages
Extra-anatomic bypass Staging possible
Least physiologic stress
Poor long-term patency
Risk of amputation
Aortic stump blowout
Graft reinfection
Need for anticoagulation
Redo in-situ prosthesis Convenience
No aortic stump
Good patency
Reinfection risk
Chronic ABX
In-situ human allograft Convenience
No aortic stump
Reinfection risk
Acute thrombosis
Chronic ABX
In-situ autogenous FPV Resistant to reinfection
Superior patency
No aortic stump
Long operation
Highest physiologic stress
Chronic ABX , Need for long-term antibiotic therapy; FPV , femoropopliteal vein grafting.

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