Physical Address
304 North Cardinal St.
Dorchester Center, MA 02124
Management of Pain in Sickle Cell Disease
~ Sickle hemoglobin results from a replacement of glutamine with valine at the sixth amino acid position in the b-globin subunit. Molecules of this abnormal hemoglobin polymerize upon deoxygenation into long polymers that physically deform the erythrocyte into the characteristic…