Spontaneous Abortion


D efinition Unavoidable loss of viability in the first 12 weeks.

Clinical Features

Epidemiology

  • Approximately one third of clinically known pregnancies terminate in the first 12 weeks.

  • Forty to fifty percent have a chromosomal anomaly.

  • Twenty percent have trisomy aneuploidies, and 6% are triploid.

  • The risk of a chromosomal abnormality increases with multiple losses.

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