Essentials

  • 1

    Australasia has a number of venomous spiders, but the majority of bites cause only minor problems.

  • 2

    Redback spider (a widow spider) bite is the most common cause of medically significant human envenoming in Australia. It can cause severe and persistent pain and, less often, systemic effects, but it is not life-threatening.

  • 3

    Australia appears to have the highest rate of widow spider envenoming (latrodectism) in the world.

  • 4

    Funnel-web spider (FWS) bite can cause life-threatening neurotoxic and cardiovascular envenoming.

  • 5

    A randomized controlled trial demonstrated that the addition of redback antivenom to standardized analgesia in patients with latrodectism did not significantly improve pain and systemic effects; and as such do not recommend using redback antivenom.

  • 6

    Antivenom to the FWS is rabbit serum based and so is less antigenic. No premedication is necessary and it is given intravenously.

Introduction

Australasia is home to a large variety of arachnids including spiders, scorpions and ticks. Spiders are the most medically important arachnids in Australasia and include redback spiders and funnel-web spiders (FWSs). FWS envenoming occurs rarely in Eastern Australia and can cause severe and potentially life-threatening neurotoxicity. Redback spider envenoming (latrodectism) occurs throughout Australia and causes a local or regional pain syndrome associated with non-specific systemic symptoms and, less commonly, autonomic effects. Other spiders that commonly cause human bites are not associated with major medical effects and include huntsman spiders (Sparassidae) , orb-weaving spiders (Araneidae) , white-tail spiders ( Lampona spp.), wolf spiders (Lycosidae) and jumping spiders (Salticidae) . FWS envenoming has resulted in death prior to antivenom, but still remains a life-threatening condition.

An approach to the patient with spider bite

Initially, a careful history should be taken to determine whether the patient has suffered a definite spider bite or only a suspected spider bite. The diagnosis of definite spider bite requires sighting of the spider at the time of the bite and usually some initial symptoms, such as local pain. If there is no history of bite or no spider was seen, then other diagnoses must be considered first. This is particularly important in persons presenting with ulcers or skin lesions with suspected spider bites ( Box 26.3.1 ). It is important in these cases that appropriate investigations are done and the case treated as a necrotic ulcer of unknown aetiology. In the majority of these cases, an infective cause is found, although less commonly they are a result of pyoderma gangrenosum or a vasculitis.

Box 26.3.1
An approach to the investigation and diagnosis of necrotic skin ulcers presenting as suspected spider bites
From Isbister GK. Spider bite. Australian Doctor 2004, with permission.

Establish whether or not there is a history of spider bite

Clear history of spider bite (better if spider is caught):

  • Refer to information on definite spider bites

No history of spider bite:

  • Investigation should focus on the clinical findings: ulcer or skin lesion

  • Provisional diagnosis of a suspected spider bite is inappropriate

Clinical history and examination

Important considerations:

  • Features suggestive of infection, malignant processes or vasculitis

  • Underlying disease processes: diabetes, vascular disease

  • Environmental exposure: soil, chemical, infective

  • Prescription medications

  • History of minor trauma

  • Specific historical information about the ulcer can assist in differentiating some conditions:

    • Painful or painless

    • Duration and time of progression

    • Preceding lesion

Investigations

Skin biopsy:

  • Microbiology: contact microbiology laboratory prior to collecting specimens so that appropriate material and transport conditions are used for fungi, Mycobacterium spp. and unusual bacteria

  • Histopathology

Laboratory investigations: may be important for underlying conditions (autoimmune conditions, vasculitis), including, but not be limited to:

  • Biochemistry (including liver and renal function tests)

  • Full blood count and coagulation studies

  • Autoimmune screening tests, cryoglobulins

Imaging:

  • Chest radiography

  • Colonoscopy

  • Vascular function studies of lower limbs

Treatment

  • Local wound management

  • Treatment based on definite diagnosis or established pathology

  • Investigation and treatment of underlying conditions may be important (e.g. pyoderma gangrenosum or diabetes mellitus)

Follow-up and monitoring

The diagnosis may take weeks or months to be established, so patients must have ongoing follow-up. Continuing management: coordinated with multiple specialties involved

If the patient has a definite history of a spider bite and has either captured the spider or has a good description of the spider, a simple approach can be taken. Health professionals should not attempt to identify spiders beyond the following simple classification:

  • redback spider

  • moderate to large black spider that is potentially an FWS in Eastern Australia

  • all other spiders.

The majority of redback spiders are likely to be identified correctly and, with supporting clinical features, this diagnosis is usually straightforward.

The second group is only important in regions where FWS are known to occur and cause significant effects (east coast of Australia from Southern Queensland to Southern New South Wales [NSW]). If the spider is large and black, then the patient should be managed as an FWS. A pressure bandage with immobilization (PBI) is the appropriate first-aid measure. The PBI should only be removed with FWS antivenom immediately available (i.e. antivenom present in the emergency department [ED] but not opened). Once in the ED they should be observed for at least 2 hours after the pressure bandage has been released or after the bite in a patient without first aid. If the patient is asymptomatic at this time, they can be safely discharged. No attempt should be made to identify the spider because the distinction between some FWS and the less significant trapdoor spiders is impossible for non-experts.

The third group includes all other spiders. Despite previous concerns about particular spiders, such as the white-tail spiders, all other spiders are very unlikely to cause more than minor effects. Patients can be reassured, their tetanus status confirmed and updated, if required, and symptomatic treatment with ice and analgesia can be offered. These patients do not need to be observed in hospital.

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