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When the first edition of this book was released, primary total knee arthroplasty (TKA) was a procedure that had a mean length of stay of around 7 days. Dr. Krackow was a pioneer and advanced the issues pertaining to length of stay throughout his career. Advances in operative techniques, anesthesia, and perioperative analgesia have allowed same-day TKA to become a reality. Outpatient total joint arthroplasty has become more popular, with goals to decrease costs while still providing high-value care. To ensure an efficient, effective, and safe outpatient TKA program, it is imperative to establish appropriate protocols. A multidisciplinary team, including the surgeon, anesthesiologist, nurses, operating room (OR) staff, and therapists, is required to set up a successful and safe outpatient total joint program.
Historically, TKA has been performed in the inpatient setting with a 5- to 10-day hospital stay. Patients remained in the hospital to be monitored for postoperative acute blood loss anemia, pain control, and mobilization with physical therapy. Improvements in pharmacological and surgical techniques have markedly reduced the operative blood loss, and fewer patients are requiring postoperative transfusions for anemia. Multimodal pain control has minimized postoperative pain, allowing earlier mobilization and early discharge. The many innovations in total joint arthroplasty and perioperative care have contributed to the successful transition of TKA to the ambulatory setting.
An estimated 680,000 TKAs were performed in the United States in 2014 and this number is expected to increase to 1.26 million by 2030 according to 2000 to 2014 trends. Policies have been instituted that have incentivized patients and physicians to reduce the cost of TKA. The most effective ways to reduce costs are by reducing the lengths of stay, complications, and readmissions. Outpatient total joint arthroplasty procedures, as a whole, have the potential to save up to $7000 per procedure compared with the inpatient setting. Medicare pays for approximately 55% of TKAs in the United States. In 2018 TKA was removed from the Medicare inpatient-only list. Since that time, there has been a marked increase in the number of TKAs done on an outpatient basis. According to Medicare Fee-for-Service Part A claims data, TKA claims went from 0.2% outpatient coding in 2017 to 36.4% in 2019.
It should be noted that there are major differences between performing a TKA in the hospital setting with the intent to discharge the patient on the same day and performing one at a stand-alone ambulatory surgery center (ASC). Even though TKA in a stand-alone ASC may be considered safe for most patients, this type of program requires a team approach from anesthesia, OR support staff, physical therapists, and nurses, with appropriate measures to account for the possible need for a 23-hour overnight stay, which may not be possible at all centers.
Multiple studies have concluded that there are no increased risks of adverse events or complications with a shorter length of stay with outpatient TKA. In a metaanalysis comparing complication rates between inpatient and outpatient total joint arthroplasties there was no increased risk of major complications, readmissions, deep venous thromboses (DVTs), urinary tract infections, pneumoniae, or wound complications with outpatient TKA. These studies suggest that arthroplasty surgeries can be performed safely in an ASC in appropriately selected patients without increased risks of complications. Kelly et al. found that patients who had surgery performed in the ASC had higher patient satisfaction scores in pain management, staff interaction, and preparedness for discharge. Thus reducing discharge delays and improving patient satisfaction scores are paramount considering the financial incentives provided by the Centers for Medicare and Medicaid Services.
Outpatient TKA may not be feasible or safe for all patients. In the same manner as for traditional TKA patients should be evaluated by their primary care physician preoperatively to note any ongoing medical problems. The first three chapters in this book focus on understanding the comorbidities of patients and how to optimize them. This is important when deciding whether a patient is a good candidate for a same-day discharge or a procedure to be done in an ASC. Patients should be medically optimized for a total joint arthroplasty by correcting modifiable risk factors. An evaluation should be performed by both the surgeon and the anesthesiologist before surgery to determine whether the patient would be a good candidate for TKA at an ASC.
Patients who have specific comorbidities, such as coronary artery disease, diabetes, body mass index (BMI) >40, peripheral vascular disease, chronic obstructive pulmonary disease (COPD), congestive heart failure, cirrhosis, chronic kidney disease, preoperative opioid use, advanced age, higher American Society of Anesthesiologists (ASA) score, and higher Charlson Comorbidity Index, have a higher risk of failure to be discharged or a higher risk of readmission. Patients with these comorbidities may not be good candidates for TKA in an ASC.
Some common criteria used for determining eligibility of patients for outpatient total joint replacement are age <70 years, ASA score I or II, primary total joint arthroplasty, hemoglobin >10 preoperatively, assistance at home, preoperative independent ambulation, and BMI <40. Some exclusion criteria commonly used are coronary artery disease, COPD, congestive heart failure, cirrhosis, chronic kidney disease, HIV positive, preoperative opioid consumption, and chronic pain syndromes (fibromyalgia). These criteria can be used as a guide, but ultimately it should be a joint decision by the patient, surgeon, and anesthesiologist.
Inclusion Criteria | Exclusion Criteria |
---|---|
Age <70 years | Chronic obstructive pulmonary disease |
Primary total knee arthroplasty | Coronary artery disease |
Body mass index <40 | Preoperative hemoglobin <10 g/dL |
Independent ambulation preoperatively | Preoperative pain syndrome or opioid dependence |
ASA score I or II | Congestive heart failure |
Appropriate assistance at home | Chronic renal disease |
When it is determined that TKA in the ASC is appropriate for a patient, it is important to adequately prepare the patient for what will be involved in the preoperative, perioperative, and postoperative settings. It is imperative that appropriate patient education be relayed not just to the patient but also to family members. A video or class that educates the patient on the importance of the preoperative steps and the postoperative risks and physical therapy guidelines can be productive. The literature presents conflicting data on preoperative education with regard to patient satisfaction, but the potential benefits and minimal harm of patient education will likely improve patient expectations. DeCook suggested multiple elements to consider with regard to patient preparation ( Table 6.1 ).
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Advances in anesthetic techniques and postoperative pain control have allowed earlier mobilization and reduced opioid consumption. Controlling pain in the early postoperative period has a profound effect on postoperative recovery in patients with TKA. Reduced pain allows more aggressive therapy and range of motion exercises in the early postoperative period, which can improve recovery and facilitate an early discharge home. Combining a neuraxial anesthetic approach, an adductor canal block, and periarticular injection can be an effective approach to minimize postoperative pain.
Postoperative pain control in patients with TKA has traditionally been a challenge. Advances in techniques and implementation of a multimodal approach to pain control have been used to maximize postoperative pain control while minimizing the side effects, particularly of opioid medications. Multimodal pain control is a comprehensive strategy for postoperative pain control that has been shown to reduce opioid consumption, adverse drug events, and lengths of stay and improve patient outcomes.
A typical multimodal pain control regimen consists of acetaminophen, a COX-2 inhibitor (celecoxib), and gabapentin to help reduce overall opioid consumption. An effective multimodal protocol begins in the preoperative period. It has been shown that preemptive administration of medications in conjunction with peripheral nerve blocks and moderate opioid doses will offer greater anesthesia than the administration of these medications postoperatively. A reasonable preoperative oral regimen on the morning of surgery may consist of 1000 mg of acetaminophen, 400 mg of celecoxib, and 300 to 600 mg of gabapentin. These medications, in addition to regional blocks, can greatly reduce pain and total opioid consumption.
In the postoperative period scheduled acetaminophen, celecoxib, and gabapentin are continued and supplemented with oral opioid analgesia. The use of tramadol for postoperative analgesia is popular, and it can be given as a scheduled dose. This is a centrally acting analgesic that acts on the opioid receptors and blocks reuptake of both norepinephrine and serotonin. Tramadol has been shown to have a lower potential for abuse, less constipation, and less respiratory depression than traditional opioids, but it comes with an increased risk of serotonin syndrome and seizures.
Oral opioids are used for ongoing pain control and breakthrough pain. Some have advocated scheduled opioid administration, with an additional dose available for breakthrough pain during the first 48 to 72 hours after surgery. Most immediate-release opioids need regular dosing every 4 to 6 hours to be most effective. When these medications are prescribed as needed, a delay in dosing such as skipping a dose overnight can cause a subsequent increase in pain. Common side effects of opioids are constipation, nausea/vomiting, and sedation. To help with these side effects, patients are also given a bowel regimen and antiemetic medications in the postoperative period.
TKA can be performed with neuraxial techniques, such as spinal or epidural anesthesia, or general anesthesia. The reported advantages of neuraxial anesthesia for TKA generally outweigh those of general anesthesia. A metaanalysis of 29 studies showed a significantly shorter length of stay with neuraxial anesthesia compared with general anesthesia, and neuraxial anesthesia is the preferred method if not contraindicated. This was further supported by Pu et al., who showed similar results of shortened length of stay and decreased nausea with spinal anesthesia compared with general anesthesia. Neuraxial anesthesia also has been associated with reduced 30-day morbidity and mortality, lower frequency of transfusions, lower risk of pneumonia, less acute renal failure, and fewer superficial wound infections. General anesthesia carries risks of respiratory and hemodynamic complications that spinal anesthesia avoids. In comparison to neuraxial anesthesia, general anesthesia was found to have increased risks of postoperative ventilator usage, unplanned reintubation, stroke, and cardiac events. General anesthesia can affect postoperative cognitive function and increase delirium in elderly patients. Neuraxial anesthesia has risks of its own, including epidural hematoma, epidural abscess, hypotension, and urinary retention. In 2019 the International Consensus on Anesthesia-Related Outcomes After Surgery (ICAROS) recommended neuraxial over general anesthesia for hip and knee arthroplasty. They found an increased risk of urinary retention but a decreased risk of mortality, pulmonary complications, acute renal failure, DVT, infections, and blood transfusions with use of neuraxial anesthesia compared with general anesthesia. Memtsoudis et al. looked at 191,570 inpatient TKAs and compared rates of inpatient falls: 10.9% received neuraxial anesthesia, 12.9% received combined general/neuraxial anesthesia, and 76.2% received general anesthesia. In conclusion, both general and neuraxial anesthetic techniques can be implemented in same-day TKA, with a preference for neuraxial anesthesia.
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