Physical Address

304 North Cardinal St.
Dorchester Center, MA 02124

Serum Sickness


Serum sickness is a systemic, immune complex–mediated hypersensitivity vasculitis classically attributed to the therapeutic administration of foreign serum proteins or other medications ( Table 175.1 ).

Table 175.1
From Aceves SS: Serum sickness. In Burg FD, Ingelfinger JR, Polin RA, Gershon AA, editors: Current pediatric therapy , ed 18, Philadelphia, 2006, Elsevier, p 1138.
Proteins and Medications That Cause Serum Sickness *

* Based on review of most current literature. Other medications that are not listed might also cause serum sickness.

Proteins From Other Species

  • Antibotulinum globulin

  • Antithymocyte globulin

  • Antitetanus toxoid

  • Antivenin (Crotalidae) polyvalent (horse serum based)

  • Crotalidae polyvalent immune Fab (ovine serum based)

  • Antirabies globulin

  • Infliximab

  • Rituximab

  • Etanercept

  • Anti-HIV antibodies ([PE]HRG214)

  • Hymenoptera stings

  • Streptokinase

  • H1N1 influenza vaccine

Drugs

Antibiotics

  • Cefaclor

  • Penicillins

  • Trimethoprim sulfate

  • Minocycline

  • Meropenem

You're Reading a Preview

Become a Clinical Tree membership for Full access and enjoy Unlimited articles

Become membership

If you are a member. Log in here

Related Posts