Refractory Scleritis in an Older Woman


History of Present Illness (HPI)

A 68-year-old woman with a history of non–insulin-dependent diabetes mellitus type 2, rheumatoid arthritis, and scleritis left eye (OS) complains of increasing pain and redness in her OS. Her scleritis has been difficult to control in the past, and last year the dosing of adalimumab was increased from 40 mg subcutaneous (SC) every 2 weeks to every week. She had to discontinue adalimumab 3 weeks ago because of an ulcer in her foot, as per the recommendations of her rheumatologist and primary care physician. Shortly after that, she reports the OS became very painful and red. She rates the pain as 8 to 9 out of 10. Her vision is a bit blurry, but she denies any major change.

Eye-Related Medications

  • Ibuprofen 800 mg by mouth (PO) three times a day (TID)

  • Adalimumab 40 mg SC every week (held as of 3 weeks ago)

Exam
OD OS
Vision 20/25 20/40
Intraocular pressure (IOP) 14 14
Lids and lashes: Normal Normal
Sclera/conjunctiva: White and quiet See Fig. 16.1
Cornea: Clear Clear
Anterior chamber (AC): Deep and quiet Deep and quiet
Iris: Flat Flat
Lens: 1+ nuclear sclerosis (NS) 2+ NS 1+ posterior subcapsular cataract (PSC)
Anterior vitreous: Clear Clear
Dilated fundus examination (DFE): Deferred

Fig. 16.1, (A) Color external photograph shows deep red injection of the inferior conjunctiva and sclera, which did not blanche with topical phenylephrine 5%. (B) Nasal view. (C) Superior view. (D) Temporal view.

Further Questions to Ask

  • What is the status of your foot ulcer? Are you on antibiotics and getting wound care? Is it almost healed?

Assessment

Diffuse anterior scleritis flare OS

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