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Red marrow: Hematopoietic marrow
Yellow marrow: Fatty marrow
Yellow marrow often distributed around central perforating vein
Yellow marrow adjacent to endplates in degenerative disc disease
After bone marrow transplantation: Fat centrally located in vertebral body, red marrow at periphery
Yellow marrow high T1W signal intensity
Red marrow low to intermediate T1W signal intensity
Signal intensity equal or slightly higher than muscle
Leukemia
Multiple myeloma
Metastasis
Myelofibrosis
Hemangioma
Normal marrow pattern changes with age
Primarily erythropoietic marrow in childhood
Gradually converts to fatty marrow during adulthood
Fatty marrow 1st seen around central draining vein
Fatty, erythropoietic marrow often intermixed in marbled pattern
Converts to predominantly fatty marrow in later adulthood
Red marrow reconversion occurs with anemia, obesity, high athletic activity, bone marrow transplantation, and erythropoietic stimulating agents
Asymptomatic
Marrow fat patterns vary with age, health
Red marrow: Hematopoietic marrow
Yellow marrow: Fatty marrow
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