Intraperitoneal Keratin Granuloma


D efinition Implants of keratinous material within the peritoneal cavity causing an associated granulomatous response.

Clinical Features

Epidemiology

  • Overall, peritoneal keratin granulomas are an uncommon finding; however, they most commonly occur in patients with gynecologic tumors.

  • The most common associated tumor is endometrioid adenocarcinoma with squamous differentiation, but squamous cell carcinoma, atypical polypoid adenomyomas, and ruptured dermoid cysts have been known to cause this finding as well.

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