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The ventricle ends in a blind pouch anteriorly called the sacculus or saccule, which is variously known as the appendix ventriculi larynges or Hilton’s sac. Laryngocele refers to a pathologic cystic dilation and enlargement of the saccule of the laryngeal ventricle. It is a rare and benign lesion of the larynx that may present with hoarseness, dyspnea, or dysphagia, depending on its size.
Laryngoceles are classified into three groups: the internal, external, and mixed type. In the internal type, the swelling is confined within the larynx. This may be seen as a swelling of the ventricle, hiding the true cord of the same side, and even extending across the midline to compromise the airway. The internal type may extend to the aryepiglottic fold and even to the base of the tongue, completely filling one vallecula.
The external type appears as a swelling in the neck, usually at about the level of the hyoid bone and just anterior to the sternocleidomastoid muscle, but can be found almost anywhere in the neck. The sacculus extends and perforates the thyrohyoid membrane where the superior laryngeal neurovascular bundle passes. This seems to be the weakest point of the membrane. In the mixed or combined type, the internal and external portions are joined by an isthmus that gives an hourglass appearance.
DeSanto classified benign cystic lesions derived from the saccule into laryngocele, laryngeal mucocele, large saccules, and laryngeal saccular cyst, depending on the size of the saccule, the presence of a communication between the saccule and the laryngeal lumen, the presence of inflammation, and the presence of symptom. They concluded that these lesions have a common pathology but show different manifestations in a developmental spectrum.
Surgical excision is indicated when the patient has apparent symptoms and a differential diagnosis is needed. A key issue is whether complete excision can be achieved without complications.
The author describes various approaches for safe surgical excision of laryngoceles.
Diagnosis and differential diagnosis are critical.
Identification of coexisting pathology is necessary.
Airway compromise should be avoided.
Temporary tracheostomy may be needed to prevent postoperative airway compromise.
Care should be taken to prevent injury to the superior laryngeal neurovascular bundle.
Careful selection of patients is important, as the surgical approach can vary according to the size and location of the laryngocele.
It is important to know that not all laryngoceles induce symptoms and not all laryngoceles should be surgically removed. Most laryngoceles are asymptomatic at onset and do not produce symptoms until they are quite large. The most common symptom is hoarseness, but the patients may also present with dyspnea or dysphagia, depending on the size of the laryngocele, or may present with a mass in the neck depending upon the location of the external laryngocele.
An asymptomatic laryngocele incidentally found on radiographic studies is not an indication for surgical treatment. Office laryngoscopy is necessary to reveal a unilateral or bilateral bulge of the false vocal fold and/or aryepiglottic fold ( Fig. 7.1 ). Examination of the ventricle is also necessary to identify synchronous pathologies that might have caused the laryngocele, but this is almost impossible to do in an office visit because the ventricular cavity is obscured by the laryngocele.
Several imaging techniques can be used to diagnose a laryngocele. Computed tomography (CT) is the gold standard, as it allows the visualization of the air-filled saccule and its anatomic relations ( Fig. 7.2 ). CT scan has proven to be the most accurate imaging method in defining the spatial relationship between the laryngocele and the laryngeal structures and extralaryngeal soft tissues, in differentiating the laryngocele from other cystic formations, and in identifying the coexistence of a laryngeal cancer.
History of present illness
Occupations: Trumpet/trombone player, glass blower, street hawker, and singer
Risk factors for laryngeal cancer: Smoking, alcohol, human papilloma virus (HPV) infection
Symptoms indicating the laryngocele status: Dyspnea, dysphonia, dysphagia, fever, pain, mass in the neck
Past medical history
Previous surgical procedures on the larynx and neck
Previous history of chronic laryngeal inflammation, such as tuberculosis and amyloidosis
Previous history of trauma to the larynx or neck
Prior treatment of larynx or neck
Previous endoscopic excision of a laryngeal mass
Previous surgery for a mass in the neck
Medical illness
Cardiopulmonary diseases
Infectious diseases
Immunosuppression, e.g., AIDS
Alcoholism and/or other substance abuse
Medications
Anticoagulants
Alcohol (risk of perioperative alcohol withdrawal syndrome)
Allergies to antibiotics
Mental and social status
Ability to give informed consent
Cosmetic consideration
Neck
Palpate both sides of the neck for the presence of a cervical mass.
Identify external component of pathology
Vertical location
Cricothyroid area
Thyrohyoid area
Valsalva maneuver
Observe size increase with/without a hissing noise.
Gentle manual palpation over the mass
Observe reduction in size with/without a hissing noise.
Identify any evidence of previous surgery.
Laryngeal endoscopic examination
Location of a bulging mass
Unilateral/bilateral
False vocal fold, ventricle, aryepiglottic fold
Coexisting pathology
Ventricular/vocal fold mass
Signs of inflammation
Vocal fold movement/mucosal lesions
General health
Cardiovascular
Respiratory
Mental
Chest radiograph
Synchronous lung pathology
Pulmonary and cardiac status
Esophagography: Only if dysphagia is present
Ultrasonography
Useful method for screening
Initial diagnostic method for a mass in the neck, differentiating the contents and location of cystic masses
CT scan
Gold standard for diagnosis and differential diagnosis
Confirms diagnosis and type of laryngocele
Differential diagnosis from other cystic benign mass and neoplasm
Magnetic resonance imaging (MRI)
Rarely indicated
Offers detailed information on the boundaries of laryngoceles: Indicated for those cases associated with a tumor of the larynx
Progressively symptomatic laryngocele
Hoarseness/breathing difficulties/swallowing difficulties
Frequent infection
Mass in the neck: Cosmetic concern
Coexisting causative pathology, suspicious for malignancy
Patient factors
Medically unfit for general anesthesia
Inability to give informed consent
Disease factors
Acute infection and inflammation
Asymptomatic laryngocele found incidentally on radiography
Evaluations by
Speech and swallowing therapist
Anesthesiology
Discontinue antiplatelet drugs if possible.
Tracheostomy if patient has progressive dyspnea
Informed consent should include the possibility of a temporary tracheostomy.
If endotracheal intubation fails
For airway obstruction
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