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Endometrial Biopsy
Description
Endometrial biopsy is an office technique used for obtaining tissue samples from the lining of the uterus. In-office techniques have largely replaced traditional dilatation and curettage.
Indications
Dysfunctional uterine bleeding, postmenopausal bleeding, menorrhagia, infertility (selected cases), endometrial or pelvic infections (eg, tuberculosis), or other situations in which a tissue diagnosis is indicated. Because it is associated with some discomfort and a small but not insignificant risk for perforation or infections and carries not only the cost of the procedure but also the cost of histologic diagnosis, this procedure is best suited for diagnosis and not screening.
Contraindications
Pregnancy, active pelvic inflammatory disease, significant vaginal infection, profuse bleeding, blood dyscrasia, obstructing cervical mass. Endometrial biopsy should generally be performed during the first 14–16 days of the menstrual cycle to avoid inadvertent disruption of an undiagnosed pregnancy; biopsies performed within 10–14 days beyond a temperature rise or luteinizing hormone surge will generally not interfere with implantation during that cycle.
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