Conversion to Open Surgical Treatment After Failed Endovascular Aortic Aneurysm Repair


Endovascular aneurysm repair (EVAR) has proved to be safe and effective for the primary treatment of aortic aneurysms. However, endoleaks, endotension, migration, and stent fracture can lead to aneurysm growth and rupture if not treated in a timely fashion. Although transition to newer-generation material and technology has improved the durability of EVAR, complications still occur. Despite the success rate of secondary interventions, patients who are not candidates for an endovascular repair or have unsuccessful interventions require conversion and explant of their endograft. As the length of follow-up increases, studies have also shown that all devices remain susceptible to the risk of removal.

The overall conversion rate is 0% to 9% based on published literature within various EVAR series. The true risk of conversion is difficult to ascertain because many patients are lost to follow-up or report to a different institution for removal. Devices that are placed outside of the instructions for use have been found to carry a higher risk of endograft failure and subsequent removal.

Differences exist between early and late conversions, which are defined as occurring before and after 30 days, respectively. A systematic literature review found that the incidence of early conversion is 0.3% to 5.9%, with a decrease in recent years. For late conversions they found that the incidence averaged 0.4% to 6.3%. In either situation, conversion to open surgery and endograft explant requires careful planning and technical skill.

Indications

The indications for early conversion are often technical from failure of deployment as a result of anatomic or contralateral gate difficulties, inadvertent coverage of renal arteries, or vessel rupture. In these circumstances, conversion is usually related to poor planning, use of devices outside of the instructions for use (IFU), or lack of technical expertise.

The indications for late explant of an aortic endograft are primarily related to device failure. This may be related to one of the many types of endoleaks with or without an enlarging aneurysm sac or migration. With the exception of a type IV endoleak, all types of endoleaks and endotension have been reported causes of aneurysm rupture. The need for explant may also be urgent or emergent as related to graft infection, including aortoduodenal fistulas, or rupture. Limb complications (such as thrombosis caused by stenoses or kinking) can also be a reason for removal when other endoluminal or surgical revascularization options do not exist.

Close monitoring of EVAR patients with secondary interventions has helped identify and, in many cases, successfully treat complications. Not all endoleaks are equal in terms of risk to the patient, and literature supports early management of type I and III endoleaks to prevent aneurysm rupture. Although endovascular salvage of EVAR complications and even recurrent rupture is a viable and often successful option for many patients, conversion is required for those that fail.

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