Yen & Jaffe's Reproductive Endocrinology

Environmental Factors and Reproduction

Acknowledgments The authors gratefully acknowledge the contribution of Patrice Sutton of PRHE and Jessica Trowbridge, MPH, UC Berkeley, who contributed to the previous (8th Edition) of this chapter. Funding to support this work was provided to UCSF’s Program on Reproductive…

Nutrition and Reproduction

Introduction In males, pulsatile gonadotropin-releasing hormone (GnRH) and gonadotropin secretion are secreted at a mean interval of every 2 hours, a frequency sufficient to maintain testosterone levels, virilization, and spermatogenesis. In females, a more complex series of gonadal tasks must…

Puberty: Gonadarche and Adrenarche

Introduction Puberty in humans is defined as the period of first becoming capable of reproducing and is distinguished by maturation of the genital organs, development of secondary sex characteristics, acceleration in linear growth velocity, changes in affect, and the occurrence…

Differences of Sex Development

Introduction Our individual sex has a major role in determining the physical attributes of our bodies, the structure of our brains, our behavioral tendencies, and our self-concept. Understanding how biological sex differences arise has both informed and been informed by…

Immunology and Reproduction

Introduction The relationship between a living organism and its environment is based on a tightly regulated balance between symbiosis and competition. Survival is dependent upon appropriate resource acquisition, permissive physicochemical environments, and competition for limiting resources and ecological niches exerted…

Male Reproductive Aging

As men age, reproductive function declines in several ways. Although the change is gradual, unlike the relatively abrupt decline that occurs in women at the time of menopause, it is progressive and probably has some adverse consequences. The decline is…

Menopause and Aging

Epidemiology The age of menopause has been constant over several centuries and is influenced by genetic, ethnic, and environmental variables. The prediction of the age of menopause based on antimüllerian hormone (AMH) trajectories is possible but impractical. Menopause is defined…

The Breast

Exclusive breastfeeding can produce amenorrhea for up to 6 months postpartum by inhibiting GnRH secretion. Breastfeeding is associated with a reduced risk of developing endometriosis, type 2 diabetes mellitus, hypertension, and breast and ovarian cancer. Introduction Structural and Histological Features…