As is the case for development of the prosencephalic structures discussed in Chapter 2 , the most critical time for development of the form and cellular structure of the brainstem and cerebellum is in the second and third months of…
Introduction The terms ventriculomegaly and hydrocephalus are often used inconsistently and imprecisely in the literature. In this discussion we use ventriculomegaly (VM) as an overarching term to describe enlarged cerebral ventricles without reference to etiopathogenesis, natural history, or outcome. Ventriculomegaly…
Normal Prosencephalic Development The major event following neurulation is development of the prosencephalon, which results in the fundamental structure of the central nervous system. The prosencephalon lies rostral to the other major vesicles of the brain—that is, the midbrain (mesencephalon)…
Introduction An understanding of the development of the nervous system is essential for an understanding of fetal and neonatal neurology. An obvious reason for this contention is the wide variety of disturbances of neural development that are flagrantly apparent in…