Valvular Heart Disease: A Companion to Braunwald's Heart Disease

Surgical mitral valve repair and replacement

Key points The mitral valve is a complex, three-dimensional assembly of independent anatomic components, including the annulus, leaflets and commissures, chordae tendineae, papillary muscles, and left ventricle. Abnormalities (lesions with etiologic implications) in any of these components may cause alteration…

Mitral valve prolapse

Key points The estimated prevalence of mitral valve prolapse (MVP) for the general population is 2.4%. The term mitral valve prolapse refers to leaflet prolapse resulting from an elongated chorda and/or leaflet. It is usually diagnosed with the use of…

Diagnostic evaluation of mitral regurgitation

Key points Transthoracic echocardiography (TTE) provides an accurate diagnosis of the cause of mitral regurgitation (MR) in most patients, although three-dimensional transesophageal imaging (TEE) often is needed for decisions about timing and type of intervention. Primary MR is caused by…

Imaging assessment for transcatheter aortic valve replacement

Key points Accurate annular sizing is critical for valve selection and minimizing complications during the performance of transcatheter aortic valve replacement (TAVR). Electrocardiogram (ECG)-gated computed tomographic (CT) angiography before TAVR is an integral part of the preprocedural evaluation of the…