Vaccine Book, The

Cancer Immunotherapy by Checkpoint Blockade

1 Introduction In the last decades there has come into being, without either flourish of trumpets or serious controversy, a general current of belief in what I have come to call ‘immunological surveillance’. – One can therefore picture a form…

Vaccines for Emerging Viral Diseases

1 Introduction Infectious diseases continue to plague mankind and evolve to keep pace with the efforts to control them. Sir William Osler captured the ongoing fear of infectious pathogens when he said, “Humanity has but three great enemies: fever, famine,…

Introduction of Vaccines Into National Programs

1 Introduction The decision for a national government to adopt a population-based health intervention such as vaccines is a complex process involving political, economic, operational/logistics, and governance issues. There are as many variations of decisions as there are the number…

Influenza Vaccines and Vaccination Strategies

1 Introduction Influenza is a communicable acute respiratory disease and one of the major infectious disease threats to the human population. Influenza virus affects individuals of all ages, causes repeated infections throughout life, and is responsible for annual worldwide epidemics…