Twining's Textbook of Fetal Abnormalities

Fetal Aneuploidies

Introduction * Acknowledgement: This study was supported by a grant from the Fetal Medicine Foundation (Charity No: 1037116). Aneuploidies are major causes of perinatal death and childhood disability. Consequently, the detection of chromosomal disorders constitutes the most frequent indication for…

First-Trimester Detection of Fetal Anomalies

Introduction The first trimester of pregnancy is generally considered to be the first 13 completed weeks. In the past, first-trimester ultrasound has mainly been used to confirm fetal viability, establish pregnancy location, count the number of fetuses and assess gestational…