Introduction The gastrointestinal (GI) tract is a rich lymphoid organ by virtue of the fact that there are numerous immune cells in the lamina propria as well as abundant lymphoid follicles and Peyer’s patches distributed throughout, which is collectively referred…
Primary Immunodeficiencies Many of the primary immunodeficiencies ( Table 5.1 ) are associated with gastrointestinal (GI) lesions. Manifestations of immune deficiency in the GI tract may be broadly divided into three categories : increased susceptibility to infection, idiopathic chronic inflammatory…
Acknowledgment The author wishes to thank Dr. Laura W. Lamps for her work on prior editions of the chapter. Introduction Gastrointestinal (GI) infections are a major cause of morbidity and mortality worldwide. As the number of transplant patients and those…
Introduction The popularity of gastrointestinal (GI) cytology for the diagnosis of infection and malignancy has waxed and waned during the past few decades. The ability to distinguish between high-grade dysplasia or carcinoma in situ and invasive carcinoma in biopsy specimens…
Introduction This chapter focuses on clinical gastroenterology issues of interest to pathologists, including endoscopic diagnosis and management of Barrett’s esophagus, management of intestinal metaplasia in the setting of chronic gastritis, and surveillance in patients with inflammatory bowel disease, colon polyps,…
Introduction Endoscopy provides a unique opportunity to visualize the mucosal surface of the gastrointestinal (GI) tract and, through endoscopic imaging techniques, a variety of extraluminal and extraintestinal organs and structures. When considered within the context of a specific clinical picture,…