Introduction Polycystic ovary syndrome (PCOS), a multifactorial disorder, involves mainly reproductive but also other endocrine systems. Based on the current Rotterdam criteria, the prevalence of PCOS varies between 5% and 10% in women of reproductive age . Metabolic issues such…
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among reproductive-aged women characterized by clinical or biochemical hyperandrogenism, oligo-anovulation, and polycystic ovarian morphology. Women with PCOS have increased risk for obesity, insulin resistance (IR), impaired glucose tolerance, type 2…
Obesity, insulin resistance and metabolic syndrome in PCOS Overweight and obesity constitute a modern global pandemic, with rapidly growing rates both in developed and in developing areas of the world. Over the last half-century, the worldwide prevalence of obesity has…
Funding sources This work was supported by the Brazilian National Institute of Hormones and Women's Health/Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq INCT grant number 465482/2014-7) and Fundação de Amparo à Pesquisa do Rio Grande do Sul (FAPERGS INCT…
Introduction Polycystic ovary syndrome (PCOS) is a very common and rather complex endocrine disorder with significant reproductive and metabolic impact . The overproduction of androgens seems to have a role in its development, hence not just being related to the…
Funding This work was supported by academic grants to Paolo Moghetti from the University of Verona. Conflicts of interest/competing interests The author has nothing to disclose. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy…
Acknowledgments Financial Support: D.H.A. and J.E.L.: NIH DK121559, HD102172, OD011106. Introduction Polycystic ovary syndrome (PCOS) is a prevalent, complex, highly heritable, subfertility health disorder of premenopausal women with numerous comorbidities . PCOS is commonly diagnosed from either revised Rotterdam or…
Acknowledgments This chapter is dedicated to Prof. Renato Pasquali, for his constant commitment to the study of PCOS. Introduction PCOS has had a complex history punctuated by a constant improvement in its understanding and evolution of diagnostic criteria . These…
Acknowledgments This work was supported by Grants PI1501686, PIE1600050, and PI1801122 from Instituto de Salud Carlos III, Spanish Ministry of Economy and Competitiveness, and co-financed by the European Development Regional Fund “A way to achieve Europe” (EDRF). CIBERDEM and IRYCIS…