Pathology of Melanocytic Tumors

Congenital Melanocytic Nevi

The term congenital melanocytic nevus (CMN) refers to a melanocytic nevus that either was present at birth or became apparent by the end of the first year of life. The term tardive CMN is used for a melanocytic nevus not…

Acquired Melanocytic Nevi

Acquired melanocytic nevi are thought to result from activation of oncogenes either through an activating mutation or translocation, allowing for clonal proliferation of the affected melanocytes. In the majority of common acquired, including the so-called dysplastic, nevi, the initiating oncogenic…

Melanotic Macules

The term melanotic macule is used to refer to benign flat pigmented lesions, which are histopathologically characterized by melanin pigment deposited in basilar keratinocytes without or at times with a slight increase in the density of solitary units of junctional…