Introduction Bone metastases are common in patients with advanced malignancies. Autopsy series have shown an incidence of bone metastases of approximately 70% in breast and prostate cancer and 35% in lung cancer. Osseous metastases can profoundly influence quality of life…
Introduction To understand metastatic disease in the abdomen and pelvis, one must appreciate the remarkable complexity of the peritoneum. By definition, the serosal peritoneum is a membrane that covers the lining of the abdominal and pelvic cavity and reflects over…
Introduction Metastasis is a complex process in which tumor cells leave the original site of disease, called the primary tumor, to spread to other parts of the body. Cancer cells can break away from a primary tumor, enter the blood…
Introduction Metastatic disease is the most common chest malignancy, and the chest acquires more metastases than any system. In autopsy series, pulmonary metastases are present in 20% to 54% of patients with a primary malignancy. The most common extrathoracic malignancies…
Introduction The lymphomas are a diverse group of hematologic neoplasms arising primarily from lymph nodes. They vary widely in affected age group, clinical course, and prognosis. Hodgkin lymphoma (HL) was first described by Thomas Hodgkin in 1832, and since the…
Introduction Myeloma and leukemia share a common origin as hematologic malignancies. Both are usually systemic at the time of the diagnosis, although occasionally a plasmacytoma may exist as an isolated collection of plasma cells without systemic involvement. Both also have…
Introduction The management of breast cancer has evolved into a highly multidisciplinary endeavor that includes specialists from medical and radiation oncology, surgery, radiology, and cancer prevention services. Despite advances in the knowledge and technology associated with diagnosis and treatment, breast…
Introduction In general, the role of imaging in ovarian cancer screening is limited, because gynecologic oncologists depend more on the clinical examination and tumor markers cancer antigen 125 (CA125) to make the diagnosis. Ovarian cancers are usually detected when patients…
Introduction Cervical cancer is the third most common gynecologic malignancy in the United States. In 2019, 13,170 new cases and 4250 deaths are expected in the United States. Across the world cervical cancer is the fourth most common cancer in…
Malignant tumors of the uterine corpus can be divided into epithelial and mesenchymal types (sarcomas). In 2019, there were an estimated 61,880 cases of cancer involving the uterine corpus in the United States, of which 3% were uterine sarcomas, with…