Nelson Textbook of Pediatrics

Schistosomiasis (Schistosoma)

The term schistosomiasis (bilharzia) encompasses the acute and chronic inflammatory disorders caused by human infection with Schistosoma spp. parasites. Disease is related to both the systemic and the focal effects of schistosome infection and its consequent host immune responses triggered…

Trichinellosis (Trichinella spiralis)

Etiology Human trichinellosis (also called trichinosis ) is caused by consumption of meat containing encysted larvae of Trichinella spiralis, a tissue-dwelling nematode with a worldwide distribution. After ingestion of raw or inadequately cooked meat from pigs (or other commercial meat…

Toxocariasis (Visceral and Ocular Larva Migrans)

Etiology Most cases of human toxocariasis are caused by the dog roundworm , Toxocara canis. Adult female T. canis worms live in the intestinal tracts of young puppies and their lactating mothers. Large numbers of eggs are passed in the…

Other Tissue Nematodes

Onchocerciasis (Onchocerca Volvulus) Infection with Onchocerca volvulus leads to onchocerciasis or river blindness . Onchocerciasis occurs primarily in West Africa but also in Central and East Africa and is the world's 2nd leading infectious cause of blindness. There have been…

Strongyloidiasis (Strongyloides stercoralis)

Etiology Strongyloidiasis is caused by the nematode, or roundworm, Strongyloides stercoralis. Only adult female worms inhabit the small intestine. The nematode reproduces in the human host by parthenogenesis and releases eggs containing mature larvae into the intestinal lumen. Rhabditiform larvae…

Enterobiasis (Enterobius vermicularis)

Etiology The cause of enterobiasis, or pinworm infection, is Enterobius vermicularis, which is a small (1 cm in length), white, threadlike nematode, or roundworm, that typically inhabits the cecum, appendix, and adjacent areas of the ileum and ascending colon. Gravid females…

Trichuriasis (Trichuris trichiura)

Etiology Trichuriasis is caused by the whipworm , Trichuris trichiura, a nematode, or roundworm, that inhabits the cecum and ascending colon. The principal hosts of T. trichiura are humans, who acquire infection by ingesting embryonated, barrel-shaped eggs ( Fig. 319.1…

Hookworms ( Necator americanus and Ancylostoma spp.)

Etiology Two major genera of hookworms, which are nematodes, or roundworms, infect humans. Necator americanus, the only representative of its genus, is a major anthropophilic hookworm and is the most common cause of human hookworm infection. Hookworms of the genus…

Ascariasis (Ascaris lumbricoides)

Etiology Ascariasis is caused by the nematode, or roundworm , Ascaris lumbricoides. Adult worms of A. lumbricoides inhabit the lumen of the small intestine. The reproductive potential of Ascaris is prodigious; a gravid female worm produces 200,000 eggs per day.…