Manual of Surgical Pathology

Small Biopsies

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Amputations and Large Resections

The most common reasons for amputations are peripheral vascular disease (with or without diabetes mellitus—account for over half of amputations), trauma, and occasionally tumors. After pathologic evaluation, an amputation specimen may be requested by the patient for burial. It is…

Adrenal Gland

Adrenal glands may be resected en bloc as part of a radical nephrectomy, to remove a clinically evident tumor (usually a functional cortical adenoma or a pheochromocytoma), or to investigate an incidental mass seen on CT scan (usually adenomas, rarely…

Microscopy and Photography

Microscopes have always been the essential tool for pathologists and will likely remain so. Although this relationship is now being questioned due to increasing reliance on digital imaging, it is important to remember that a tissue section is a three-dimensional…

Occupational Hazards

A pathology department potentially can be a dangerous place to work. Hazards related to the profession include physical injury (scalpel cuts, needle sticks), infectious disease, radioactivity, and noxious chemical fumes. However, the most common health-damaging risks are associated with long…

Special Studies

The pathologist’s H&E (hematoxylin and eosin) is like the clinician’s H&P (history and physical)—basic examinations performed on every specimen or patient forming the cornerstone of diagnosis. A wide variety of additional special studies are available to evaluate pathologic processes, from…

Requests for Pathologic Evaluation

As our knowledge deepens about the molecular underpinnings of disease, the need for precise and optimal pathologic evaluation increases. The pathologist has an essential role in patient care as guardian of the integrity and quality of specimens, diagnostician, patient advocate,…