CLINICAL PEARLS Surgical resection plays a key role in curative-intent treatment of patients with stages I, II, and IIIA NSCLC. Prior to resection, patients should be assessed for mediastinal lymph node involvement by PET/CT, and pathological nodal assessment by EBUS…
CLINICAL PEARLS Resectability is determined by patient fitness to undergo surgery and tumor characteristics. Appropriate tumor staging, especially mediastinal nodal involvement, is fundamental to surgical planning. Pulmonary function testing must be performed to determine whether a patient can tolerate loss…
CLINICAL PEARLS The field of molecular pathology is rapidly moving toward noninvasive and digital methods of detection as theragnostic biomarkers are being used to guide cancer management. Biomarker testing has now become the pillar of treatment decision for advanced-stage non−small…
CLINICAL PEARLS Establishing an appropriate histological diagnosis and stage of lung cancer is critical to avoid delays in treatment. Noninvasive staging plays an important role in the initial clinical staging of lung cancer and includes imaging such as computed tomography…
CLINICAL PEARLS Lung cancer mortality has been declining since the 1990s, yet it remains the leading cause of cancer mortality and is still expected to cause more than 120,000 deaths in 2023 in the United States. National and local efforts…