Hematology: A Pathophysiologic Approach

Hematopoiesis

Key points Hematopoiesis begins in the embryonal yolk sac and aorto-gonado-mesonephros (AGM), migrates to the fetal liver and spleen, and then moves to the bone marrow by birth. The nonhematopoietic marrow stroma provides a microenvironment conducive to growth and differentiation…