Gynecologic and Obstetric Pathology

Maternal Floor Infarct/Massive Perivillous Fibrin Deposition

D efinition — Diffuse or multifocal fibrin deposition that fills and obliterates the intervillous space along a significant portion of the chorionic plate. Clinical Features Epidemiology Uncommon (less than 1% of placentas). Occasionally associated with abnormal maternal clotting (APhA, ATIII…

Amniotic Bands

D efinition — Detached strips of amniotic membrane that restrict fetal growth, resulting in asymmetric anomalies that do not follow a recognized developmental pattern. Clinical Features Epidemiology One in 2,500 to 10,000 deliveries. You’re Reading a Preview Become a Clinical…

Fetal Vascular Thrombosis

PITFALL D efinition — Thrombus formation within the umbilical cord, within its tributaries on the placental surface, or within stem villi. Clinical Features Epidemiology Common; seen in 3% to 10% of placentas. Increased incidence with maternal diabetes. You’re Reading a…

Circummarginate and Circumvallate Placentas

D efinition — Variations in membranous insertions on the placental disk. Clinical Features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here

Single Umbilical Artery (SUA)

D efinition — Umbilical cord with two vessels; one umbilical artery and one vein. Clinical Features Epidemiology Common; noted in 1% to 3% of all gestations. More frequent in spontaneous abortions. More frequent in white women than black or Asian…

Knots in the Umbilical Cord

D efinition — True knots in the umbilical cord. Clinical Features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here

Chorangioma

D efinition — Benign expansile nodule of capillaries and stromal cells. Clinical Features Epidemiology Uncommon; this finding is seen in less than 0.5% of placentas. Associated with twin gestations and preeclampsia. You’re Reading a Preview Become a Clinical Tree membership…

Epithelioid Trophoblastic Tumor

D efinition — A subset of extravillous trophoblastic tumor that is thought to arise from an extravillous (transitional) trophoblast that forms a transition from villous cytotrophoblast to mature extravillous trophoblast. These cells are found in the chorionic membrane, maternal surface…