Glioblastoma

The Molecular Pathogenesis of Glioblastoma

The cellular origin of glioblastoma is complex. Despite decades of research, the understanding of the cellular, molecular, and pathogenetic architecture of this lethal disease is still evolving. Other chapters discuss the epidemiology, risk factors, associated clinical outcomes, and molecular targeting…

The Story of Glioblastoma: History and Modern Correlates

Glioblastoma remains a formidable pathologic entity. Without the tools necessary to make a neurologic diagnosis, early medical and surgical clinicians were likely not only puzzled but also appalled by the downward trajectory of patients affected by this tumor. The development…