Drugs During Pregnancy and Lactation

Antiepileptics

4.8.1 Introduction All antiepileptics pass into the milk, albeit in differing amounts. Babies who are breastfed during maternal antiepileptic treatment apparently develop just as well as those who are not breastfed. At least, that is what was reported in one…

Cardiovascular drugs and diuretics

There are cardiovascular drugs and diuretics that can be used during pregnancy and lactation. The decision to continue these medications during lactation depends on many factors. Some of these factors include the well-being of the mother, the blood/milk barrier, the…

Vaccines and immunoglobulins

4.5.1 Maternal immunization A woman who has not received all the recommended immunizations before or during pregnancy may be immunized in the postpartum period even though she is breastfeeding. The presence of live viruses in the milk does not present…

Anti-infectives

With many antibiotics, a breastfed child receives less than 1% of the weight-related therapeutic dose when the mother is being treated. Thus only minimal concentrations – and in no case, bacteria-inhibiting concentrations – are achieved in the infant’s plasma. The…

Gastrointestinal drugs

Medications used to treat gastrointestinal symptoms are often prescribed during breastfeeding. However, there is little information describing the transfer into human milk for many of these drugs. Some of the gastrointestinal agents can be administrated during breastfeeding: antacids, sulcrafate, Helicobacter…

Antiallergics, antiasthmatics and antitussives

Second-generation antihistamines which have practically no sedative effect are compatible during breastfeeding. First-generation antihistamines with sedating action should be reserved during breastfeeding for special conditions. Should adverse effects such as restlessness or mild sedation occur, the consequences are to be…

Analgesics, antiphlogistics and anesthetics

Paracetamol and ibuprofen are the drugs of choice for treating pain and their use requires no limitation of breastfeeding. Continuous treatment with acetylsalicylic acid is not recommended and selective COX-2 inhibitors should be avoided because of limited experience on their…