Dorfman and Czerniak's Bone Tumors

Benign Osteoblastic Tumors

Benign osteoblastic tumors were first recognized as a distinct group by Jaffe and Mayer in 1932. The identification of osteoid osteoma as a separate entity came later in a 1935 report by Jaffe. Once osteoid osteoma had been established as…

Molecular Biology of Bone Tumors

During the past two decades, our knowledge of the molecular events that are responsible for the development and progression of many human neoplasms, including those that affect the skeleton, has dramatically improved. This has been made possible by numerous technologic…

Clinical Considerations and Imaging of Bone Tumors

Introduction Bone lesions lend themselves to radiographic assessment because of the fact that bone has a built-in contrast agent, the calcium hydroxyapatite crystal. Much information about bone destruction, bone production, matrix calcification and ossification, and the reactive response of the…

General Considerations

Introduction The new edition of this book retains the conventional approach to the classification of bone tumors, dividing them into the categories of osteoblastic, chondroblastic, fibrous and fibroosseous, vascular and neurogenic, and others of mesenchymal tissue derivation. In general, the…