Key Concepts Boston keratoprosthesis type 2 implantation can provide sustained improvement of vision in a select, high-risk population of patients, but is associated with significant complications and requires lifelong postoperative care. The Boston keratoprosthesis type 2 is reserved for patients…
Key Concepts The Boston keratoprosthesis type 1 is a viable therapeutic option for patients who have previously failed penetrating keratoplasty and increasingly as a first-line option for patients at high-risk for conventional keratoplasty. The visual outcomes of keratoprosthesis implantation are…
Key Concepts The keratoprosthesis (KPro) may have expanded indications, but there remain many difficulties in its postoperative management. The KPro is not ideal for patients with severe ocular surface disease, such as Stevens-Johnson syndrome, mucous membrane pemphigoid, and severe chemical…
Key Concepts Keratoprosthesis is a reasonable option in eyes not amenable to conventional keratoplasty. Advances in the design of the Boston keratoprosthesis type 1, such as the titanium back plate, have improved outcomes. Changes in the postoperative management of the…
Key Concepts Success of the Boston type 1 keratoprosthesis (KPro) begins with a thorough preoperative evaluation. The Boston type 1 keratoprosthesis is assembled from a front plate and stem made from polymethylmethacrylate (PMMA), a corneal graft, a back plate made…
Key Concepts Widespread use of keratoprosthesis devices has led to indications of improved vision in many patients with no other treatment options. The prognosis for keratoprosthesis recipients can be classified into three main groups, in decreasing order of success: (a)…
Key Concepts Corneal crosslinking (CXL) could be considered an adjunct treatment in infectious keratitis. CXL should be considered in cases of severe unresponsive infectious keratitis. Indirect benefits of CXL, such as corneal melting improvement, may help clinical and visual outcomes…
Key Concepts Corneal collagen crosslinking (CXL) is a treatment designed to decrease the progression of keratoconus and postrefractive ectasia. Maximum keratometry generally stabilizes and flattens, on average, by approximately 1.6 and 0.7 D after CXL for keratoconus and ectasia, respectively.…
Key Concepts Corneal collagen crosslinking (CXL) has become the mainstay of treatment to prevent progression of keratoconus (KCN). The standard Dresden protocol involves epithelial removal, a 30 minute topical application of riboflavin, followed by a 30-minute ultraviolet light exposure. Multiple…
Key Concepts Management of the underlying disease is critical to the successful management of scleral perforations. Multiple options and materials are available for the surgical closure of scleral perforations. The physician should consider the use of homologous materials for repair…