Comprehensive Guide to Hidradenitis Suppurativa, A

Hidradenitis Suppurativa—Other Procedural Treatments

Introduction The treatments for hidradenitis suppurativa (HS) can generally be divided into those with pharmacologic focus, and those that are procedural. For milder Hurley stage I disease, management is usually medication-focused, and designed to control or prevent the inflammatory events.…

Laser and Light Treatments for Hidradenitis Suppurativa

Abbreviations: hidradenitis suppurativa (HS) carbon dioxide (CO 2 ) neodymium-doped yttrium aluminum garnet (Nd:YAG) Hidradenitis Suppurativa Clinical Response (HiSCR) Dermatology Life Quality Index (DLQI) photodynamic therapy (PDT) methyl aminolevulinate (MAL) 5-aminolevulinic acid (ALA) methylene blue (MB) Introduction In additional to…

Operative Techniques for Hidradenitis Suppurativa

History of Surgery in Hidradenitis Suppurativa Hidradenitis suppurativa (HS) was first described by two surgeons in the 1800s, Velpeau and Verneuil. There was much debate surrounding whether HS was primarily a venereal disease, tumor, or abscess. In the 1890s, Barthelemy…

Office-Based Non-Excision Procedures

Introduction In the last few decades, surgical interventions for hidradenitis suppurativa (HS) have expanded well beyond traditional excisional approaches with the popularization of deroofing, the use of electrosurgical and laser-based excisions, and combined approaches that take both medical and surgical…

Quality of Life

Introduction Hidradenitis suppurativa (HS) is characterized by relapsing, painful, suppurating, bleeding nodules, abscesses, and sinus tracts that primarily affect intertriginous skin. Aside from its debilitating physical manifestations, the disease carries a profound psychological burden and socioeconomic impact. These factors contribute…

Pain and Itch Control

Introduction Pain is the most burdensome symptom of hidradenitis suppurativa (HS), accounting for greater impairment in HS-related quality of life (QoL) than even disease severity. Although it has received relatively less attention, pruritus is also common in HS and contributes…

Targeted Therapeutics: Biologics, Small Molecules

Introduction Hidradenitis suppurativa (HS) is a chronic inflammatory disorder with a complex, multifactorial, and incompletely elucidated pathophysiology. Among relevant host factors are a number of important inflammatory pathways, including increased production of oxygen free radicals, enhanced expression of toll-like receptors…

Non-Antibiotic and Non-Biologic Systemic Therapeutics

Introduction The pathogenesis of hidradenitis suppurativa (HS) remains to be fully elucidated. Genetic susceptibility along with hormonal fluctuations and immune dysregulation are all thought to contribute to HS development. HS tends to occur in patients with comorbid conditions associated with…