Clinical Cardiac Electrophysiology

Electroanatomic mapping and magnetic guidance systems

Electroanatomic mapping Theoretical considerations During conventional electrophysiology (EP) procedures, catheters are manually navigated with the use of single or bi-plane fluoroscopy. An inherent limitation of fluoroscopic navigation is that orientation of the catheter relative to the cardiac anatomy can only…

Electrophysiology hardware

Electrode catheters Basic mapping catheters Catheters used for electrophysiology studies (EPSs) and ablation are composed of multiple insulated wires encased in woven Dacron or polyurethane. Electrodes used in electrophysiology (EP) catheters are usually made of polished platinum-iridium alloy. Platinum is…

Vascular access and catheter placement

Patient preparation Patients should be studied in the postabsorptive state and after beta blockers or other antiarrhythmic agents have been discontinued for at least 5 days. Amiodarone should be withdrawn at least 2 months before the procedure if feasible. A…

Cardiac anatomy for the electrophysiologist

Some of the descriptive terms conventionally used for cardiac structures are inaccurate. Conventionally the heart and its associated structures have been described in accordance with their position when the heart has been removed from the body and positioned with the…

Electrophysiologic mechanisms of arrhythmogenesis

Normal excitation of the heart Cardiac electrical activity starts by the spontaneous excitation of “pacemaker” cells in the sinoatrial node in the right atrium. Pacemaker automaticity is due to spontaneous diastolic repolarization of phase 4 that generates rhythmic action potentials…

Classification of arrhythmias

Bradyarrhythmias are due to sinus nodal disease ( Box 1.1 ) or atrioventricular conduction block ( Box 1.2 ). Box 1.1 Sinus Node Dysfunction (with accompanying symptoms) Sinus bradycardia Sinoatrial exit block Sinus pauses (>3 s) Sinus node arrest Tachycardia-bradycardia…