Basic Science in Obstetrics and Gynaecology

Pathology

General Pathological Principles Adequate understanding of the underlying pathophysiological disease processes associated with the range of obstetric and gynaecological presentations is essential for the rational evaluation of appropriate investigations, therapies and outcomes. Huge volumes of literature are available on almost…

Applied Anatomy

Introduction This chapter will address general anatomical principles as well as cover detailed anatomy relevant to the obstetrician and gynaecologist and the Membership of Royal College of Obstetricians and Gynaecologists (MRCOG) exams. Particular attention is given to how this knowledge…

Fetal and Placental Physiology

Introduction The subject of fetal and placental physiology encompasses a large and complex branch of the reproductive sciences, and any one of the subsections below could form the subject of an entire textbook. The concepts described here should aid the…

Embryology

Oogenesis and Spermatogenesis The process of fertilisation involves the union of female and male gametes, the ovum and spermatozoon, respectively. In humans there is a ready supply of spermatozoa constantly available from the normal healthy male after the age of…

Clinical Genetics

Clinical genetics is the specialty concerned with the diagnosis and investigation of disorders which are thought to have a genetic basis. The clinical genetics team is multidisciplinary and consists of consultants and specialist registrars working closely with genetic counsellors and…

Structure and Function of the Genome

This chapter will provide a basic introduction to the human genome and some of the tools used to analyse it. Genomics and molecular biology have developed rapidly during the last few decades, and this chapter will highlight some of these…