KEY FACTS

General

  • Amputation and disarticulation should be viewed as reconstructive procedures and not a failure of treatment.

    • In this manner, one realizes that it is the initial step in getting patients back to their previous functional status.

  • Indications for amputation include ischemia, trauma, infection, tumor, and painful dysfunction of the foot and ankle not amenable to further conservative management.

  • The goal is to create a modified limb that has a comfortable interface with a prosthesis and offers the most efficient energy-conserving gait as possible.

  • A team effort, with a team composed of different medical specialists, is the best way to ensure a good result and restore patients to their optimal level of function.

  • It is important to be aware of the psychosocial recovery of the patient with an amputation.

  • Functional outcome is generally worse in patients with diabetes or end-stage renal disease.

Important Points for Surgical Approach to Amputation

  • Team assessment

  • Atraumatic soft tissue handling

  • Adequate skin flaps

  • Myodesis or myoplasty whenever possible

  • Nerve transection sharp and at level well above amputation

  • Artery and vein dissected free and double ligated

  • Closure without tension

  • No "dog ear" resection

  • Accept delayed primary closure if there is tension

USA amputation statistics by cause is shown. [From Adams PF et al. (1999) Current estimates from the National Health Interview Survey, 1996. Vital Health Stat 10: 200.]

Myodesis consists of suturing the transected muscle to the bone through drill holes.

The cut ends of antagonistic muscle groups and their fascias are sewn together for myoplasty.

Equivalent-length dorsal and plantar full-thickness fish mouth-type skin flaps should be created, thus favoring the tougher plantar skin for the end of the stump.

Indications

Peripheral Vascular Disease

  • Peripheral vascular disease (PVD) is the most common reason for amputation.

    • Affects mainly geriatric patients and those with diabetes mellitus.

  • Up to 20% of patients with diabetes mellitus will suffer from PVD.

    • Patients are prone to develop foot ulcers leading to lower extremity amputation.

  • Peripheral neuropathy increases risk of complications.

    • Loss of protective sensation compromises the likelihood of healing ulcers.

  • Prior to considering amputation, vascular studies are useful to determine the following:

    • Possibility of revascularization

    • Level of amputation

  • 25% of diabetics who undergo amputation will require an amputation on the contralateral limb within the following 3 years.

  • Because of the medical complexity of these patients, optimal management is multidisciplinary with a team composed of a primary care physician, internist, surgeon, physiatrist, physical therapist, prosthetist, and social worker.

    • The input of an infectious diseases specialist may also be required.

  • PVD accounts for 90% of amputations with 97% of dysvascular amputations performed on the lower limb.

  • African American males are at greatest risk for dysvascular amputation.

    • They are 2-4x more likely to lose a limb than white persons of similar age and gender.

  • In amputees with PVD, the 5-year survival rate is between 70-90% with heart disease as the leading cause of death (51%).

    • This is possibly because the coronary heart vessels are subject to the same occlusions as the peripheral arteries.

  • Approximately 50% of dysvascular amputees are diabetic.

Civilian Trauma

  • Several well-established scoring systems have been developed to help in arriving at a decision to perform an immediate amputation following lower extremity trauma.

  • A commonly used scoring system is the Mangled Extremity Severity Score, which consists of 4 categories: Skeletal/soft tissue injury, limb ischemia, shock, and age.

    • A lower number of points indicates a less severe injury.

    • A total score of 7 or below is almost always compatible with limb salvage.

  • It is felt by some that soft tissue injury severity has the greatest impact on decision-making regarding limb salvage vs. amputation.

  • There are several other proposed limb salvage scoring systems.

  • While they may provide guidance for a treating surgeon, none of the scoring systems are considered very reliable in predicting need for amputation.

  • In cases of severe limb damage, primary amputation at first surgery may be best for the patient’s physical and psychologic well-being.

  • In other cases, it may be better to plan an initial attempt at limb salvage and observe.

    • Prolonged attempts at limb salvage lead to severe psychologic and economic burdens on the patient and the family.

  • If it is thought that amputation is inevitable, it should be performed as a delayed primary amputation within the first 10-14 days after injury.

  • Almost 70% of trauma-related amputations are upper limb amputation.

  • The most common causes of lower extremity trauma requiring amputation are lawn mower injuries and motorcycle accidents.

  • Traumatic amputees have a better functional prognosis than dysvascular amputees.

Military Trauma

  • The changing nature of military conflicts over the past few decades has lead to an increasing number of blast injuries.

    • A mangled extremity is a common combat injury.

  • While advances have been made in limb salvage of complex injuries, amputation sometimes offers the best outcome.

  • In several studies of wounded soldiers, immediate and delayed lower extremity amputation patients generally have better functional outcomes compared to limb salvage, both physically and psychologically.

    • This is not true for every patient but rather represents a trend for the groups as a whole.

    • Individual decisions are made based on the extent of injury, the experience of the surgeon, and the capabilities of the health care system.

    • Immediate amputation may be necessary for a critically ill patient in a combat zone, whereas the same injury in a stable patient at a tertiary center may be offered limb salvage.

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