Adrenocorticotropic Hormone Stimulation Test

Background

The adrenocorticotropic hormone (ACTH) stimulation test is a relatively noninvasive laboratory assessment that involves the administration of a medication followed by the collection of blood samples. ACTH is a naturally occurring hormone released from the pituitary gland that stimulates the secretion of cortisol from the adrenal glands. Cortisol is a glucocorticoid that is responsible for the regulation of fat, carbohydrate, and protein metabolism. The test is extremely valuable, as it is safe and reliable in the diagnosis and assessment of adrenal insufficiency. Other names for this test include corticotropin or cosyntropin stimulation test, or short Synacthen test.