Acute Abdomen


The term acute abdomen refers to the signs and symptoms of abdominal pain and tenderness. This situation often represents an underlying surgical problem that requires prompt diagnosis and surgical treatment. While the ready availability of diagnostic studies such as computed tomography (CT) scans or magnetic resonance imaging (MRI) has added greatly to our ability to accurately diagnose most of the conditions responsible for the acute abdomen, the mainstay for diagnosis remains a good history and physical exam complemented by laboratory and radiologic studies as appropriate. In addition, many conditions that are not surgical or even centered in the abdomen can also cause this presentation. A prompt and accurate diagnosis is necessary in order to select the appropriate therapy, which may be a laparoscopy or laparotomy.

Age, gender, and a history of prior abdominal surgical procedures are associated with different problems causing the acute abdomen. Certain diseases like appendicitis and mesenteric adenitis are more common in the young while biliary tract disease, diverticulitis, and intestinal ischemia are more common in older populations. Chapter 67 deals with abdominal pain in children.

Numerous problems that are not surgical may also present as an acute abdomen. These include endocrine and metabolic issues, hematologic problems, and disorders caused by toxins or drugs ( Box 46.1 ). , Endocrine and metabolic diagnoses include uremia, diabetic or Addisonian crisis, acute intermittent porphyria, hyperlipoproteinemia, and hereditary Mediterranean fever. Hematologic disorders include sickle cell crisis and acute leukemia. Toxins and drugs that can cause acute abdominal pain are lead and other heavy metal intoxications, narcotic withdrawal, and black widow spider bites. All of these need to be considered when evaluating a patient with sudden onset abdominal pain.

Box 46.1
Nonsurgical causes of the acute abdomen.

Endocrine and Metabolic Causes

  • Acute intermittent porphyria

  • Addisonian crisis

  • Diabetic crisis

  • Hereditary Mediterranean fever

  • Uremia

Hematologic Causes

  • Acute leukemia

  • Sickle cell crisis

Toxins and Drugs

  • Black widow spider poisoning

  • Lead poisoning

  • Other heavy metal poisoning

  • Narcotic withdrawal

The need for prompt surgical treatment of those causes of the acute abdomen that require operation mandates an expeditious evaluation so that the proper therapy can be carried out ( Box 46.2 ). A focused history and physical examination and indicated laboratory and imaging studies will then allow for the correct diagnosis and guide appropriate therapy. While imaging studies have added greatly to the accuracy of the diagnosis of causes of the acute abdomen, a thorough history and careful physical examination remain the mainstays of evaluation.

Box 46.2
Surgical acute abdominal conditions.

Hemorrhage

  • Aortoduodenal fistula after aortic vascular graft

  • Arteriovenous malformation of the gastrointestinal tract

  • Bleeding gastrointestinal diverticulum

  • Hemorrhagic pancreatitis

  • Intestinal ulceration

  • Leaking or ruptured arterial aneurysm

  • Mallory-Weiss syndrome

  • Ruptured ectopic pregnancy

  • Solid organ trauma

  • Spontaneous splenic rupture

Infection

  • Appendicitis

  • Cholecystitis

  • Diverticulitis

  • Hepatic abscess

  • Meckel diverticulitis

  • Psoas abscess

Ischemia

  • Buerger disease

  • Ischemic colitis

  • Mesenteric thrombosis or embolism

  • Ovarian torsion

  • Strangulated hernia

  • Testicular torsion

Obstruction

  • Cecal volvulus

  • Gastrointestinal malignancy

  • Incarcerated hernias

  • Inflammatory bowel disease

  • Intussusception

  • Sigmoid volvulus

  • Small bowel obstruction

Perforation

  • Boerhaave syndrome

  • Perforated diverticulum

  • Perforated gastrointestinal cancer

  • Perforated gastrointestinal ulcer

Anatomy and Physiology

Abdominal pain is visceral, parietal, or referred. The presentation for each helps determine the source of the pain. Visceral pain is vague and localized to the epigastrium, periumbilical region, or lower abdomen, depending on whether it originates from the foregut, midgut, or hindgut. Visceral pain is usually due to the distention of a hollow viscus. Parietal pain is sharper and better localized than visceral pain and corresponds to the nerve roots that supply the peritoneum. Referred pain is perceived at a site distant from the source of the pain. Common sites of referred pain and their sources are listed in Box 46.3 . Determining whether the pain is visceral, parietal, or referred can usually be accomplished with a careful history.

Box 46.3
Locations and causes of referred pain.

Left Shoulder

  • Heart

  • Left hemidiaphragm

  • Spleen

  • Tail of pancreas

Right Shoulder

  • Gallbladder

  • Liver

  • Right hemidiaphragm

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