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Pain is a multifaceted and complex experience, with both sensory and emotional components.
When pain persists beyond the expected time of healing, chronification of pain occurs and is best treated within a biopsychosocial framework.
National physician treatment guidelines recommend nonpharmacological treatments, such as exercise therapy and psychological therapies (cognitive behavioral therapy [CBT] and mindfulness-based therapy), as the first-line approaches to chronic low back pain.
CBT for pain (CBT-P) centers on the bidirectional relations between one’s thoughts and beliefs, emotions and physiological responses, and behaviors and pain.
Treatment goals for CBT-P are to reduce overall pain, suffering, and disability by improving patient self-management skills,
The efficacy of CBT-P for chronic pain is well-established. A shift in empirical investigations to understand the factors which predict the best response to CBT-P is needed.
Promising adaptations of CBT-P are emerging (such as digitized interventions and early intervention in the subacute and/or perioperative period). These approaches offer the potential to improve accessibility and treatment engagement, as well as reduce the risk for chronification of pain.
Most spine pain is self-limiting, resolving on its own without treatment or intervention. Despite this established finding, chronic back pain (defined as pain of ≥12 weeks ) has high prevalence rates and societal burden, and is thus a significant public health issue. Two-thirds of the population experience chronic back pain at some point in their lives. The costs of low back pain are estimated to be around $200 billion yearly within the United States, and low back pain is now considered to be the number one cause of disability globally. High-impact chronic pain (HICP) is a term recently used to more fully capture the pain experience. HICP addresses not only pain duration (i.e., ≥3 months), but also includes activity participation and limitations. The primary focus of this chapter is to identify and describe therapeutic treatment interventions for individuals living with high-impact chronic back pain.
The International Association for the Study of Pain defines pain as “an unpleasant sensory and emotional experience associated with actual or potential tissue damage, and described in terms of such damage.” This definition of pain recognizes the subjective emotional experience associated with pain and underscores the fact that psychology is inherent in the definition of pain. To fully treat the experience of pain one must acknowledge the psychological factors, such as emotions, attention, and behavioral reactions, that occur in conjunction with the sensory experience. For example, many individuals become fearful of worsening pain with activity and are overly vigilant to cues of pain. This model of fear-avoidance is theorized to maintain pain and pain-related fear. Patients also may develop unhelpful ways of thinking and responding to the pain experience. For example, pain catastrophizing, defined as “an exaggerated negative mental set brought to bear during actual or anticipated painful experiences” is comprised of three domains–helplessness, magnification, and rumination –and is consistently linked to a number of poor pain outcomes, including higher pain sensitivity, disability, opioid use, and development of chronic pain and depression. , Lastly, patients living with persistent pain may develop anxiety or depressive disorders that add to the patient’s difficulty in managing pain. These psychological factors will be discussed in further detail in subsequent sections of this chapter.
The recommended treatment for chronic pain has changed over time as the biological, as well as psychosocial, factors that maintain pain have been elucidated. For most patients, it is not solely the experience of pain that can lead to debilitation, but the combination of biological, psychological, and social factors.
When addressing chronic pain, there is a shift away from pain elimination. Pain reduction is treated as secondary to improving function and decreasing disability, improving mood, and reducing fear avoidance and pain catastrophizing. Historically, opioids were used for the treatment of acute pain and cancer-related pain; however, the past few decades saw an explosion in long-term opioid therapy for chronic noncancer pain. Many factors have been postulated to contribute to the opioid epidemic; however, the combination of increased opioid prescribing with little oversight, aggressive marketing campaigns, and the call to treat pain as “the fifth vital sign” are key variables in the subsequent rise in opioid use disorders and overdose deaths within the United States. Although well-meaning at the outset, long-term opioid therapy now is established as largely ineffective for those experiencing chronic, persistent pain. , In an effort to combat the consequences of long-term opioid use, new guidelines and policy changes have shifted to focus evaluation and treatment on biopsychosocial interventions that address not only biomedical factors associated with persistent pain but also psychosocial factors. This change paralleled the emphasis on self-management strategies, including cognitive behavioral therapy (CBT), as a first-line treatment for chronic low back pain. With this shift in treatment came a change in relevant treatment outcomes. Concurrently, guidelines for research and outcome studies were developed with more rigorous and multidimensional components. For example, the Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials recommends core outcome domains, including “pain, physical function, emotional functioning, participant rating of improvement, symptoms and adverse events, and participation disposition,” as key treatment pain-related outcomes for clinical trials. ,
The chronification of acute pain leads to a “chronic pain experience” that encompasses biological, affective, cognitive, and behavioral variables , that interact and over time may result in a “pain identity.” Whereas traditional biomedical treatment approaches are likely to be more effective for acute pain, they may be insufficient when dealing with a complex, multifactorial condition such as chronic pain. Biopsychosocial frameworks for chronic pain treatment address the personal, social, and economic burden , experienced by those living with chronic pain. Traditional medical models aim to treat pain as a symptom of a disease process; however, the biopsychosocial model addresses not only biological factors that play a role in the experience of pain but also psychosocial stressors. Psychosocial factors, considered to be the strongest predictors of pain-related outcomes , must be considered in treatment approaches for chronic pain.
CBT is largely recommended as a stand-alone treatment intervention or in conjunction with other treatments for chronic pain due to the lasting effects, longstanding efficacy, and minimal side effects. , CBT for pain is guided by the theoretical framework established by Dr. Aaron Beck, the originator of CBT, who postulated that distress (or psychopathology as it was initially developed for) stems from cognitive misinterpretations of the world, self, or others. CBT for pain similarly addresses how one’s thoughts and feelings influence behaviors relate to the experience of pain ( Fig. 74.1 ).
CBT-P is also heavily influenced by the gate control theory of pain, which was the first theory of pain that emphasized the role of psychology. The gate control theory revolutionized pain science by suggesting that the modulation of the dorsal horn in the spine is controlled by a “gate,” ultimately modifying the output of the transmission of cells in the spinal cord. The “gate” is opened and closed through ascending and descending nerve fibers, and ultimately is controlled by the brain. It is proposed that various factors have the ability to open the gate, which ultimately increases the flow of pain signals and pain perception, whereas when the gate is closed, it decreases the flow and intensity of the pain signals. Factors that contribute to an open gate may include poor coping skills, trauma, inactivity, depression, anxiety, stress, pain catastrophizing, and/or pain-related fear. Factors that contribute to a closed gate may include healthy coping, psychophysiological self-regulation, exercise, and engaging in pleasurable activities. The gate control theory offered a greater understanding to the role of cognitive, emotional, and behavioral factors in the experience of pain, and underscored the ability of psychological experiences in changing the flow of pain signals. Further conceptualizations of pain, such as the neuromatrix concept, have expanded upon the gate control theory, addressing some of its limitations such as the underemphasis on the interacting pain areas in the brain and how pain is represented centrally. The neuromatrix theory emphasizes cognitive, affective, and sensory influences on pain. , These neural components play a vital role in the brain’s ability to modulate pain responses, as well as contributing to pain perception. This system allows the brain to determine if a sensation experienced is threatening or dangerous.
Additional theoretical influences on the application of CBT to pain include applied learning and behavioral theories. Wilbert Fordyce, a psychologist, considered the role of social experiences and environmental factors in shaping the chronic pain experience. His model of pain included the impact of patients engaging in “pain behaviors” (e.g., guarding or bracing) and how these behaviors become dysfunctional and lead to disability as they are reinforced over time.
A variety of psychological interventions may be used to address the biopsychosocial correlates of chronic pain, depending upon the patient’s treatment needs. As noted, one of the most prominent and rigorously studied approaches is CBT–a skills-based, time-limited treatment modality. CBT-P centers on the bidirectional relations between all of these factors and pain, with interventions specifically addressing these three components. The common goals for CBT-P are to reduce overall pain, suffering, and disability by improving patient self-management skills. Through this treatment, patients acquire adaptive self-regulatory skills such as cognitive restructuring to extinguish maladaptive thoughts and beliefs, relaxation techniques to improve autonomic control, and activity pacing to approach activities in a safe and sensible manner. , CBT-P identifies unhelpful responses to pain and invites patients to address the various opportunities they have to break their cycles of pain (see Fig. 74.1 ). CBT-P uses common treatment components across patients, but there are a variety of skills that may be added or removed based on the patient’s individual needs, and there is an art to its implementation. The skill-based interventions discussed in the next section are a selection of the most commonly utilized, but do not represent all possible options.
Pain is indisputably a biopsychosocial phenomenon, therefore it is important for patients to understand the role of these three aspects (biology, psychology, and the social environment) in their pain experience. Patients’ frustration with lack of effective treatment options, feelings of helplessness, and fear of worsening pain, along with the seemingly negative impact on their future, are fueled by poor understanding of the chronic pain disease process. Patients often approach self-management of chronic pain similarly to acute pain, with rest, guarding behavior, and limited activity. This response stems from the belief that pain is always an indication of tissue damage and that the severity of pain is linearly related to the amount of tissue damage in the body, both of which have been debunked. , To foster motivation and confidence in CBT-P and challenge misinformation about pain, patients require education about their condition and the factors that impact it. In fact, evidence suggests that pain education alone may even be sufficiently effective in producing changes in pain perception.
When introducing CBT-P, treatment often starts with outlining the difference between acute and chronic pain, highlighting the increasing role of the central nervous system in the continued maintenance of pain (i.e., central sensitization), and incorporating the biopsychosocial model of pain as it relates to the patient’s specific symptom presentation. Discussion of central sensitization in a palatable way allows for patients to recognize that their pain is not simply related to injury but instead a complex set of changes to their nervous system. When patients have an understanding of the disease model of chronic pain, it becomes easier for them to understand the role of psychology and how CBT-P may be effective for them.
Chronic pain acts as a persistent physical and emotional stressor, resulting in continual activation of the sympathetic nervous system, similar to that of any long-term stressors. As such, pain and stress share an important mechanism that can be dually addressed with psychophysiological training and biofeedback. Psychophysiological training teaches individuals to identify and self-regulate their pain and stress responses and employ relaxation to promote autonomic changes and central nervous system modifications. Psychophysiological training and biofeedback may reduce pain in certain pain conditions; , however, it is more closely associated with improved coping. A foundational tool, diaphragmatic breathing, teaches patients how to slow their breathing, breathe more fully and efficiently by engaging their diaphragm, and increase oxygen in the system. This change in breathing activates the parasympathetic response, increases activity in the cortical and subcortical areas, and results in reduced symptoms of arousal, anxiety, depression, anger, and confusion. This technique may be paired with other training techniques, including progressive muscle relaxation (i.e., focused and systematic tensing and relaxing of muscle groups) and guided imagery (i.e., focused imaginal exercise involving each of the senses to induce a feeling of calm). Biofeedback may be used to assist the patient in identifying the physiological signs of stress and relaxation. With or without biofeedback, relaxation training offers benefits in the treatment of pain and is a simple, low-risk, and drug-free method for managing pain and stress.
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