Central Spinal Cord Syndrome


KEY FACTS

Terminology

  • Central cord syndrome (CCS), acute traumatic central cord syndrome (ATCCS)

  • Most common partial cord syndrome

  • Traumatic cord injury, with clinical syndrome of

    • Bilateral weakness, arms > legs

    • Bladder dysfunction, variable sensory loss

  • Injury to central gray matter, corticospinal and spinothalamic tracts

Imaging

  • Radiographs may show spondylosis or congenitally diminished canal diameter

  • MR shows hyperintense signal in central spinal cord on T2WI

  • Significant percentage shows fracture/dislocations

Pathology

  • Often with preexisting canal stenosis

    • Congenital canal stenosis

    • Disc herniation, osteophyte

    • Facet/ligamentous hypertrophy

Clinical Issues

  • 4 groups

    • 10% of ATCCS patients have MR evidence of cord signal change with no other radiographic abnormality

      • Medical management

    • 20% of ATCCS patients present with acute disc herniation

      • Surgical intervention recommended

    • 30% of ATCCS patients have cervical spine fracture subluxation injuries

      • Early realignment of spinal column with spinal cord decompression is recommended

    • 40% of ATCCS patients have spinal stenosis without evidence of bony or ligamentous injury

      • Management remains controversial

Sagittal reformatted spine CT shows focal flexion deformity at C5-C6
with splaying of the posterior elements
, demonstrating a hyperflexion injury in this trauma patient with marked upper extremity weakness.

Sagittal T2WI of the same patient again shows the focal flexion deformity at C5-C6. There is extensive moderately hyperintense signal in the cord from C2-C3 through C6-C7
, demonstrating contusion within the spinal cord. Also note edema within prevertebral soft tissues
.

Lateral radiograph in this injured child presenting with central cord syndrome shows borderline thickening of the prevertebral soft tissues
but is otherwise unremarkable.

Sagittal T2WI MR in the same child shows a normal vertebral column and prevertebral soft tissues (seen better on other sequences). There is extensive hyperintense signal within the cord from the cervicomedullary junction
through T4-T5
demonstrating spinal cord contusion.

TERMINOLOGY

Abbreviations

  • Central cord syndrome (CCS), acute traumatic central cord syndrome (ATCCS)

Synonyms

  • Partial cord syndrome (subset of)

Definitions

  • Most common partial cord syndrome

  • Traumatic cord injury, with clinical syndrome of

    • Bilateral weakness, arms > legs

    • Bladder dysfunction

    • Variable sensory loss

  • Injury to central gray matter, corticospinal and spinothalamic tracts

IMAGING

General Features

  • Best diagnostic clue

    • Hyperintense signal in central spinal cord on T2WI

  • Location

    • Predominates at C3-C4 through C5-C6 levels

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