Mesh at the Hiatus


Crural repair and reduction of hiatal hernia (HH) are paramount to the success of an antireflux surgery. Case series from the early laparoscopic era (i.e., the 1990s) reported an unacceptably high recurrence rate of HHs. In addition, some patients were found to be naturally predisposed to hernia formation, and recurring hernias were thought to be due in part to inherent defects in healing. Simultaneously, the routine use of synthetic mesh in inguinal and ventral hernia repair was gaining widespread acceptance and was found to be both safe and effective.

These findings set the stage for some practitioners to advocate for the use of mesh at the hiatus. Soon thereafter, several case series described experience with various types of synthetic mesh materials and configurations of mesh at the hiatus, and these studies were strengthened by significantly lower recurrence rates in their series. However, these early reports were followed by isolated case reports describing complications related to mesh use, including catastrophic cases that required esophagogastric resections. These disastrous complications were thought to result from the synthetic nature of the mesh materials being used, so bioprosthetic materials were suggested as attractive alternatives to synthetic mesh. A randomized prospective trial described outcomes in patients with and without use of biologic mesh and found a significant decline in recurrence at 6 months’ follow-up when mesh reinforcement was used. A large series of 28 patients undergoing reoperation with either synthetic or biologic mesh at the hiatus was published that demonstrated that both types of mesh were associated with significant mesh-related complications. Since then, others have reported that reoperation after the use of mesh is significantly more challenging than reoperation in patients in whom mesh was not used and that the patients with mesh are at greater risk of needing an esophagogastric resection.

Perhaps the benchmark for HH repair, with or without mesh, is the sizable open transthoracic series by Maziak et al. They achieved a mean follow-up of 94 months in 90 of 94 patients in their cohort who underwent surgical repair of a large paraesophageal hernia (PEH) over a 36-year period. They reported excellent results in 72 of 90 patients (80%), with anatomic recurrence in only two patients, both of whom underwent reoperation. Table 30.1 summarizes the findings of studies on open PEH repair with objective follow-up.

TABLE 30.1
Open Hiatal Hernia Repair
Author, Year Study Design Findings
Maziak et al., 1998 94 patients with massive incarcerated PEH. Mean follow-up: 94 months. 93% of patients had good or excellent outcome; only 2% had symptomatic recurrence.
Low and Unger, 2005 72 patients with large PEH. Mean follow-up: 29.8 months. 18% of patients had recurrent hernia. No patient required revision surgery.
PEH , Paraesophageal hernia.

Since the publication of these early laparoscopic reports, advancements in minimally invasive surgery (e.g., improved visualization, better instrumentation, and greater experience) have helped surgeons achieve more extensive mediastinal dissection, better crus closure, and use of Collis gastroplasty. All of these are associated with improved outcomes with primary crus repair of the hiatus, even for larger HHs. The goal of this chapter is to briefly review the advantages and disadvantages of using mesh at the hiatus.

Hiatal Hernia: Recurrence and Outcomes

Recurrence Rates With Primary Closure in the Early Laparoscopic Era

A 2004 review described a high recurrence rate of eight HH case series published up to that point. The studies that were evaluated incorporated systematic radiographic follow-up for laparoscopic PEH repair, and objective follow-up was available for 277 of 460 patients. The mean overall reported recurrence rate was 27% (range, 7% to 43%). In 2000 Hashemi et al. reported their experience with 54 patients who underwent surgery for repair of large PEH at the University of Southern California, a large and well-respected esophageal center. In the subset of patients who underwent laparoscopic repair of large PEH ( n = 27), objective follow-up was available for 21 patients (78%). These authors found HH recurrence in 9 of 21 patients (43%), with 8 of 21 patients (38%) also reporting recurrent symptoms. This report led to widespread uncertainty about the safety and efficacy of laparoscopy for PEH repair. However, the authors' high rate of recurrent symptoms is unusual because most patients who undergo laparoscopic PEH repair report good to excellent symptom control, which may not correlate with radiographic recurrence.

Recurrence Rates With Primary Closure in the Modern Laparoscopic Era

Andujar et al. reported their systematic radiographic follow-up for 166 patients who underwent laparoscopic repair of large PEH. At a mean follow-up of 15 months, they stated a recurrence rate of 25% (5% PEH and 20% sliding HH). Nine years later, Gibson et al. described the outcomes of their single-center experience of HH repair in 100 consecutive patients. They reported a very low recurrence rate of 9 of 100 patients, 7 of whom had only a small (<2 cm) recurrent HH. The same group later reported medium-term follow-up, describing a total recurrence rate of 25% at mean follow-up of 24 months (5% PEH and 20% small HH). They also reported excellent continued gastroesophageal reflux disease–related quality-of-life scores.

Nason et al. reported their long-term follow-up of 187 patients who underwent laparoscopic repair of a giant PEH from 1997 to 2003. Over their median follow-up of 77 months, they found a radiographic recurrence rate of 15%. Mittal et al. later reported 5-year follow-up findings in their 73 patients who underwent surgical intervention for intrathoracic stomach. They reported 5%, 11%, and 17% radiographic failure rates at 1, 3, and 5 years, respectively, after surgery. Table 30.2 summarizes outcomes after laparoscopic PEH repair.

TABLE 30.2
Laparoscopic Hiatal Hernia Repair
Author, Year Study Design Findings
Hashemi et al., 2000 54 patients: 13 open surgery, 14 thoracotomy, 27 laparoscopic HH repair. Symptomatic outcomes: excellent/good in 76% laparoscopic; 88% in open. Recurrence in 12 patients, symptomatic in 5/12. (Laparoscopic 42% recurrence, open 15% recurrence).
Mattar et al., 2002 136 patients: Laparoscopic PEH repair. Mean follow-up: 40 months. Significant improvement of all symptoms. Three patients had symptomatic recurrence.
Targarona et al., 2004 Review of eight case series. Objective follow-up for 277 of 460 patients. Mean overall recurrence rate: 27% (range, 7%–43%).
Ferri et al., 2005 60 patients: 25 open surgery, 35 laparoscopic HH repair. Recurrence rate: 44% open, 23% laparoscopic.
Rathore et al., 2007 Meta-analysis of 13 retrospective reviews. 965 patients. Overall recurrence rate for laparoscopic PEH repair: 10.2%. True recurrence rate with video barium esophagram 25.5%. No associated learning curve. Hiatoplasty and esophageal lengthening had significant protective influence.
White et al., 2008 10-year follow-up for 52 patients with laparoscopic PEH repair. Significant improvement in symptoms at 10 years compared with preoperative symptoms. Ten recurrences (2 within 1 postoperative year).
Luketich et al., 2010 662 patients with laparoscopic giant PEH repair. Mesh and Collis use decreased over time with stable morbidity rates. QOL scores were excellent or good in 90%; radiologic recurrence in 16%. Symptomatic recurrence in none. Reoperation in 3%.
Mittal et al., 2011 73 patients with ITS, 7 transthoracic, 64 laparoscopic, 1 open, 1 laparoscopic-to-open conversion. Mesh used in 14%. Objective failure at 1, 3, and 5 years was 5%, 11%, and 17%, respectively. Subjective outcome was similar at each follow-up period. Subjective satisfaction remained high throughout follow-up.
Le Page et al., 2015 455 patients with attempted laparoscopic repair of giant HH. Mean follow-up: 42 months. Laparoscopy in 95% (mesh in 6%). Overall recurrence: 35.6%; follow-up at over 10 years: 50%. Recurrence in 14.8%; revision surgery in 4.8%.
HH , Hiatal hernia; ITS , intrathoracic stomach; PEH , paraesophageal hernia; QOL , quality of life.

You're Reading a Preview

Become a Clinical Tree membership for Full access and enjoy Unlimited articles

Become membership

If you are a member. Log in here