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Electrosurgery harnesses electricity with the intention of creating various thermal effects to achieve resection, incision, hemostasis, and devitalization of target tissues. The therapeutic basis of all electrosurgery is the production of thermal energy at the cellular level, typically as a result of a high-frequency alternating current created by an electrosurgery generator or unit.
Heat generated by this process is the result of resistance or impedance to the flow of electricity within the tissue. The electrical current must alternate (i.e., change direction between positive and negative) at a frequency of more than 100,000 times per second (100,000 Hz) to avoid the neuromuscular responses and shocks that occur with the typical 60-Hz household current. The process, however, should not be termed “electrocautery,” as this is a misnomer referring merely to the ability to “burn” with electricity. “Electrosurgery” provides both cutting and coagulation, making it the ideal technology for producing therapeutic coagulation, resection, and tissue ablation throughout the gut. When the current density is sufficient within the targeted tissue, cellular water is rapidly heated, resulting in boiling and bursting of cellular membranes. When this energy is directed along a blade or wire, the result is electrosurgical cutting. At lower current densities, a less intense reaction results in tissue coagulation and desiccation without cutting.
Electrosurgery has widespread use in multiple endoscopic applications, such as polypectomy, hemostasis, and tissue resection. The advent of flexible duodenoscopes and miniaturized electrosurgical tools allows electrosurgical applications to be applied to endoscopic retrograde cholangiopancreatography (ERCP), permitting sphincterotomy, tumor ablation, and intracorporeal stone destruction (lithotripsy). Present and future applications require a thorough understanding of electrosurgery.
Electrosurgery was first introduced in Europe in 1923 by ERBE Elektromedizin GmbH (Tübingen, Germany) and in the United States in 1926 by William Bovie and Harvey Cushing. In the 1960s and 1970s, electrosurgical units (ESUs) became an absolute mainstay in medical care, but without formal education regarding their use, many physicians experienced the catastrophic potential of an inadequately understood technology. It was not uncommon, for example, to experience return pad and alternate-site burns. Although burns can never be totally eliminated when using ESUs, the current “isolated systems” work with safety features in the generator to help prevent such injuries. They also have preprogrammed modes and microprocessors, allowing for intelligent control of the current.
Electrosurgical technologies were first introduced to ERCP in 1974 when Kawai and Classen independently published case series of endoscopic sphincterotomy followed by stone extraction. Classen described the use of “a special high-frequency diathermy knife,” essentially a miniaturized electrosurgical tool with cutting properties. The field was young, but the benefits of endoscopy with electrosurgical potential were immediate.
ESUs have become more complex, but also more intelligent and arguably safer. For years it was difficult to account for all of the electrical variables and achieve consistently reproducible results. However, the introduction of regulated electrosurgery in the 1980s by the ERBE Company (ERBE Elektromedizin GmbH) was a significant advance. Modern ESUs now continuously monitor current and voltage, calculate parameters such as power and tissue resistance from these, and analyze these findings in milliseconds. Depending on the desired effect, these parameters are kept constant or modulated by the ESU. Electrosurgery, therefore, has become widespread and safe in its current form. The potential for danger, however, is still present and arises from a poor understanding of the technology, especially when the desired tissue effect is not achieved.
Basic laws of physics govern the behavior of electricity, and, as such, its behavior is predictable. There are four variables that can be used to describe a circuit and are entirely interdependent: resistance (R), voltage (V), current (I), and power (P). In its simplest form, a circuit must include a power source, a resistive element, and a path for the flow of current. Electrical current is defined as the flow of electrons, as measured in amperes or amps, through a circuit in response to an applied electromotive force termed voltage. Resistance or impedance represents the obstacle to the flow of current and is measured in ohms. The flow of current through a conductor is governed by Ohm's law, which ties together current (I), voltage (V), and resistance (R):
It states simply that current increases as voltage increases for a constant resistance and that current decreases as resistance increases for a constant voltage. The relationship is predictable. Another simple relationship is represented by P = VI = I 2 R, where P is the power generated in a circuit. Power is the transfer of energy and is measured in watts and rate per second as expressed in joules (watt-seconds). The ability of a current to do work is a result of the energy potential stored in a circuit, which is then dissipated at specific points, usually at the site of a resistor. In our human circuit, the tissue acts as the resistor and the power used is dissipated as thermal energy. The rise in temperature is governed by Joule's law:
where Q is the heat generated by a constant current (I) flowing through a conductor of electrical resistance (R) for a time (t). When electrosurgery is applied to a tissue, the effect, whether it is cutting or coagulation, depends directly on Q.
In a typical monopolar endoscopic circuit, the electrosurgical generator serves as a voltage source. An active electrode, in this case a sphincterotome, conducts electrons to the patient. The patient acts as a resistive element. Electrons come back via the patient return electrode to the ESU. A power setting is present on the electrosurgical generator. This power is a representation of the amount of work the circuit will do at the point of contact. As noted above, because the power is set as a constant and the resistance is inherent to the human tissue, the generator will intelligently try to control the current and the voltage accordingly.
Electrosurgery uses high-frequency alternating current, which may alternate polarity or direction up to 500,000 times a second. The cutting and coagulation effects that are desired in electrosurgery occur when the frequency is in the lower radiofrequency range of 300,000 to 1 million Hz. Modern ESUs contain microprocessors that not only control the frequency, voltage, and current but also calculate the impedance of the tissue in contact with the electrode. These ESUs have at least one selection that attempts to hold power constant as closely as possible to the selected watts over a broad range of impedances. As tissue desiccates and fulgurates, impedance increases and an ESU that can dynamically adjust for changing impedance within a tissue can also control for unwanted effects. For example, constant and consistent power during polypectomy helps reduce against snare entrapment as the snare begins to close and the current density increases. During sphincterotomy, as the wire shortens, the area of tissue contact may diminish and impedance rises as tissue desiccates; constant power allows for a controlled cut rather than a “zipper cut.”
In addition, modern ESUs are “isolated” and keep current flow within the contained circuit to capture the current through the return plate. If the circuit is broken, no current will flow at any point within the system. An isolated ESU has a transformer that causes the current to return only to the generator and not use alternate pathways to return to its source. If this is not possible, the generator will shut down. An isolated ESU prevents alternate-site burns, but not patient return electrode burns.
Generators typically use one of two types of circuit—monopolar or bipolar. Monopolar circuits use the body between the active electrode and the grounding pad to complete the circuit back to the ESU ( Fig. 11.1 ). Bipolar circuits are complete within the electrosurgical tool itself by containing both electrodes in close proximity. Both monopolar and bipolar circuits have specific uses and advantages in endoscopy.
In monopolar circuits, the return plate, dispersive pad, grounding pad, and neutral electrode are essential because they collect the electrosurgical energy from the patient and return it safely to the generator. Without a return plate, there is no circuit and the electrosurgical device will do no work. Additionally, the return plate, which is situated externally on the patient's skin, becomes an active part of the circuit, which in the past created potential for return-site burns. The energy returned, however, is of low current density, minimizing or eliminating this effect, but it can still potentially occur if the plate is poorly sited.
The benefit of a monopolar device is its ability to achieve high levels of thermal effect with the versatility to cut and coagulate. Examples of the monopolar mode in endoscopy are polypectomy snares, sphincterotomes, needle knifes, ESD tools, and argon plasma coagulation. Although the bipolar mode does not require a grounding pad, the thermal effect is localized only to the tissue in direct contact with the device electrode. The advantage of this mode is the precise delivery of intense energy into a small space, such as in a bipolar hemostasis probe or electrohydraulic lithotripsy fiber.
Both types of circuits are similar, in that their result depends directly on the current density achieved by the tool at the site of the targeted tissue. Current density is the result of several variables but, in essence, represents the density of energy within a given electrical space. Given a constant amount of energy being generated, as when a sphincterotomy wire shortens or a snare closes, the current density increases. Current density is lower when spread over a greater volume of tissue, and the resulting effect will be slower heating. Energy spread over a ball tip or flat forceps jaw promotes coagulation by reducing the current density, as opposed to concentrating current along a snare or sphincterotome wire that promotes cutting.
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